{"podcast":{"title":"Metabolic Mind","slug":"metabolic-mind-6253550","podcast_index_feed_id":6253550,"rss_url":"https://feeds.captivate.fm/metabolic-mind/","website_url":"https://metabolicmind.org/","image_url":"https://artwork.captivate.fm/d5c870fb-4d35-464f-8bde-33ce9e2b58c4/MM-Podcast-cover-final.png","author":"Bret Scher","episode_count":224,"summary":"Metabolic Mind is working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. Metabolic interventions like ketogenic therapy are being used to treat serious mental illnesses like Bipolar Disorder, Schizophrenia, and Major Depressive Disorder. We explore topics that can help you understand how Metabolic Psychiatry might help you or a loved one treat mental disorders Watch our videos at https://www.youtube.com/@metabolicmind Our channel is for information only. Consult your physician before changing your lifestyle or medications.","last_synced_at":"2026-07-24T00:18:08.497488+00:00","page_url":"https://stenobird.com/podcast/metabolic-mind-6253550"},"episode":{"title":"New Study from 25-Year Eating Disorder Expert","slug":"new-study-from-25-year-eating-disorder-expert","published_at":"2026-06-05T15:04:00+00:00","page_url":"https://stenobird.com/podcast/metabolic-mind-6253550/new-study-from-25-year-eating-disorder-expert","show_page_url":"https://stenobird.com/podcast/metabolic-mind-6253550","url":"https://metabolicmind.org/","audio_url":"https://episodes.captivate.fm/episode/7ec4a0ea-c3ee-4d8f-be01-cfe4808e36db.mp3","summary":"Anorexia nervosa has one of the highest mortality rates of any psychiatric illness, yet effective biological treatments remain limited. For many people living with the condition, even after successful weight normalization, persistent psychological symptoms, including obsessive thoughts about food, shape, and weight, continue to drive relapse. In this conversation, Dr. Bret Scher sits down with Dr. Guido Frank, Professor of Psychiatry at UC San Diego with over 25 years of experience in eating disorder treatment, to discuss results from the first-ever clinical trial of ketogenic therapy in anorexia nervosa. This 14-week supervised feasibility trial enrolled 22 individuals with weight-normalized anorexia nervosa. Among the 18 study completers: ✅ 72% scored in the recovered range on eating disorder assessments, no longer meeting the criteria for an anorexia nervosa diagnosis ✅ 100% of study completers saw improvements in depression symptoms, with 72% scoring within the normal range. ✅ Participants did not experience significant weight change throughout the study In this conversation, Dr. Frank also discusses: What led a self-described skeptic to investigate ketogenic therapy for anorexia nervosa How the study was structured, who it enrolled, and what the weekly supervision looked like What participants experienced as symptoms improved, including reports of mental clarity and relief How weight remained stable throughout the ketogenic intervention The pushback from colleagues and how to engage with the skepticism What comes next, including ongoing brain imaging research and plans for a randomized controlled trial Early observations in bulimia nervosa and what they may suggest about metabolic factors in eating disorders This trial demonstrated that ketogenic therapy is well t…","meta_description":"Anorexia nervosa has one of the highest mortality rates of any psychiatric illness, yet effective biological treatments remain limited. For many people li…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2143,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/metabolic-mind-6253550/episodes/new-study-from-25-year-eating-disorder-expert/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/metabolic-mind-6253550/new-study-from-25-year-eating-disorder-expert.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}