{"podcast":{"title":"Lung Cancer Update","slug":"lung-cancer-update-827388","podcast_index_feed_id":827388,"rss_url":"https://feeds.captivate.fm/lung-cancer-update/","website_url":"https://www.researchtopractice.com/browse-tumor-types/lung-cancer","image_url":"https://artwork.captivate.fm/230421a8-7e2e-4fb0-b40c-3b50a1cbf78f/nstTehQJgx-Rm0qFgD_28hl9.png","author":"Dr. Neil Love","episode_count":56,"summary":"Featuring one-on-one interviews conducted by Dr Neil Love, this series bridges the gap between research and patient care by providing medical oncologists, hematologists and hematology/oncology fellows ongoing access to the perspectives and opinions of national and international research leaders with an expertise in thoracic oncology.","last_synced_at":"2026-07-15T06:20:06.840223+00:00","page_url":"https://stenobird.com/podcast/lung-cancer-update-827388"},"episode":{"title":"Nonmetastatic Non-Small Cell Lung Cancer — An Interview with Dr Jamie E Chaft","slug":"nonmetastatic-non-small-cell-lung-cancer-an-interview-with-dr-jamie-e-chaft","published_at":"2026-07-11T13:00:00+00:00","page_url":"https://stenobird.com/podcast/lung-cancer-update-827388/nonmetastatic-non-small-cell-lung-cancer-an-interview-with-dr-jamie-e-chaft","show_page_url":"https://stenobird.com/podcast/lung-cancer-update-827388","url":"https://lung-cancer-update.captivate.fm/episode/6094-oncologytodaynmnsclc26","audio_url":"https://dts.podtrac.com/redirect.mp3/episodes.captivate.fm/episode/6ff846e2-343d-4d25-b48f-33eac2454707.mp3","summary":"Featuring an interview with Dr Jamie E Chaft, including the following topics: Case: A man in his early 70s with a 40 to 50 pack-year history of smoking and cT2bN1 squamous cell carcinoma of the lung with PD-L1 60% treated with induction therapy and surgery (00:00) Available clinical data with immunotherapy in the neoadjuvant, perioperative and adjuvant settings (07:45) Factors in the selection of adjuvant immunotherapy, including circulating tumor DNA (11:39) Evolving approaches to management, including systemic therapy, surgery and radiation therapy techniques (19:28) Case: A woman in her early 60s with nonmetastatic non-small cell lung cancer (NSCLC) and an EGFR exon 19 deletion who is enrolled in the NeoADAURA study (24:03) Importance of clinical trials in the adjuvant setting (33:02) Data surrounding treatment in the neoadjuvant setting; key implications of the NeoADAURA study (35:41) Case: A man in his late 60s with a history of smoking and Stage III T4N3 NSCLC not otherwise specified with low PD-L1 expression, high tumor mutation burden, microsatellite stability and an STK11 mutation (41:34) Selecting patients for the NeoADAURA study treatment approach; deciding between chemoimmunotherapy and chemoradiation therapy (51:01) CME information and select publications","meta_description":"Featuring an interview with Dr Jamie E Chaft, including the following topics: Case: A man in his early 70s with a 40 to 50 pack-year history of smoking an…","key_points":[],"chapters":[],"topics":[],"duration_seconds":3595,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/lung-cancer-update-827388/episodes/nonmetastatic-non-small-cell-lung-cancer-an-interview-with-dr-jamie-e-chaft/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/lung-cancer-update-827388/nonmetastatic-non-small-cell-lung-cancer-an-interview-with-dr-jamie-e-chaft.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}