{"podcast":{"title":"Legacy and Longevity Podcast","slug":"legacy-and-longevity-podcast-7476055","podcast_index_feed_id":7476055,"rss_url":"https://legacyandlongevity.com/rss","website_url":"https://legacyandlongevity.com/","image_url":"https://storageapi.podup.com/production/2324/podcastsettings/53f24df30e5876a9d639f66d5c8e0e38fd44e49e.png","author":"Zach Dancel","episode_count":42,"summary":"Zach Dancel sits down with world-class thinkers, leaders, and innovators to uncover the mindset, habits, and science behind living stronger, leading with purpose, and creating something that lasts far beyond yourself. This isn't just another health show—it's a blueprint for building an extraordinary life. In every episode, Zach explores the lessons, disciplines, and breakthroughs that fuel greatness in both health and leadership. From cutting-edge functional and longevity medicine to the mindset strategies of elite performers, the conversations challenge you to raise your standards, strengthen your body and mind, and pursue a legacy that endures. You'll hear from visionary leaders who've built impact-driven careers, top longevity experts breaking down the science of living a longer, healthier life, peak performers sharing what it takes to lead with purpose and resilience, and real people who've transformed their health, mindset, and future against the odds.","last_synced_at":"2026-07-22T06:21:01.072535+00:00","page_url":"https://stenobird.com/podcast/legacy-and-longevity-podcast-7476055"},"episode":{"title":"Does TRT Cause Heart Attacks? What the FDA's 5,000-Man Trial Just Proved (with Stephanie Misanik)","slug":"does-trt-cause-heart-attacks-what-the-fda-s-5-000-man-trial-just-proved-with-stephanie-misanik","published_at":"2026-05-26T14:30:00+00:00","page_url":"https://stenobird.com/podcast/legacy-and-longevity-podcast-7476055/does-trt-cause-heart-attacks-what-the-fda-s-5-000-man-trial-just-proved-with-stephanie-misanik","show_page_url":"https://stenobird.com/podcast/legacy-and-longevity-podcast-7476055","url":"https://legacyandlongevity.com/podcast/does-trt-cause-heart-attacks-what-the-fdas-5000-man-trial-just-proved-with-stephanie-misanik-1","audio_url":"https://traffic.podup.com/media/storageapi.podup.com/production/2324/files/files/episode-33-longevity-steph_part-2.mp3?key=eyJkb21haW4iOiJsZWdhY3lhbmRsb25nZXZpdHkuY29tIiwicHQiOiJwb2RjYXN0IiwicHMiOiJkb2VzLXRydC1jYXVzZS1oZWFydC1hdHRhY2tzLXdoYXQtdGhlLWZkYXMtNTAwMC1tYW4tdHJpYWwtanVzdC1wcm92ZWQtd2l0aC1zdGVwaGFuaWUtbWlzYW5pay0xIiwia3kiOjExNywid2kiOjF9","summary":"Does TRT cause heart attacks? For 70 years, doctors said yes. The FDA's 5,000-man Traverse trial just settled it. Here's what every man on or considering testosterone replacement therapy needs to hear. In this continuing episode of the Legacy and Longevity Podcast with host Zach Dancel, Stephanie Misanik, Clinical Director at Nava Health, to dismantle the cardiovascular myth that's kept a generation of men sick. They unpack the flawed 2013 JAMA study that scared millions, the bodybuilder dosing error that built the modern fear, what the Traverse trial actually proved about TRT and heart health, and why the \"normal\" testosterone range your doctor uses is based on the sickest population in history. 🎙️ Zach and Stephanie share: 🚨 The 2013 JAMA study flaw that scared millions of men from testosterone for over a decade 🔬 What the FDA's 5,000-man Traverse trial just proved about TRT and cardiovascular risk 💉 The bodybuilder dosing error that ruined testosterone's reputation for ordinary men 📉 Why \"normal\" testosterone ranges are calibrated to the sickest population in American history 👶 How to preserve fertility while on TRT (and the medications that make it possible) 🏋️ The gym-influencer lie that's keeping suffering men out of treatment 🧠 Why men often don't realize they have low testosterone until it's gone ⚡ The real benefits of optimized testosterone for heart, brain, bone, and muscle 🩺 Why the 305 ng/dL patient is being failed by conventional medicine every day 💊 How often to actually inject testosterone (and why most clinics get it wrong) You will hear why everything your doctor told you about testosterone and your heart was built on bad science. And what the FDA just proved instead. Watch the full conversation with Stephanie Misanik on The Legacy and Longevity Podcas…","meta_description":"Does TRT cause heart attacks? For 70 years, doctors said yes. The FDA's 5,000-man Traverse trial just settled it. Here's what every man on or considering…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2609,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/legacy-and-longevity-podcast-7476055/episodes/does-trt-cause-heart-attacks-what-the-fda-s-5-000-man-trial-just-proved-with-stephanie-misanik/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/legacy-and-longevity-podcast-7476055/does-trt-cause-heart-attacks-what-the-fda-s-5-000-man-trial-just-proved-with-stephanie-misanik.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}