{"podcast":{"title":"HCPLive Podcasts","slug":"hcplive-podcasts-19526","podcast_index_feed_id":19526,"rss_url":"https://audioboom.com/channels/5004077.rss","website_url":"https://audioboom.com/channels/5004077","image_url":"https://audioboom.com/i/40144427.png","author":"HCPLive.com","episode_count":243,"summary":"Your destination feed for medical, health care and clinical science podcasts courtesy of HCPLive—featuring our shows Medical Ethics Unpacked, New Insight, and 5 Stories in Under 5.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/hcplive-podcasts-19526"},"episode":{"title":"Liver Lineup: Innovations in Cholestatic Disease Management, With Kris Kowdley, MD","slug":"liver-lineup-innovations-in-cholestatic-disease-management-with-kris-kowdley-md","published_at":"2026-02-03T21:47:21+00:00","page_url":"https://stenobird.com/podcast/hcplive-podcasts-19526/liver-lineup-innovations-in-cholestatic-disease-management-with-kris-kowdley-md","show_page_url":"https://stenobird.com/podcast/hcplive-podcasts-19526","url":"https://audioboom.com/posts/8856585","audio_url":"https://audioboom.com/posts/8856585.mp3?modified=1770155320&sid=5004077&source=rss","summary":"In this episode of Liver Lineup: Updates & Unfiltered Insights , host Nancy Reau, MD, sits down with Kris Kowdley, MD, to discuss evolving approaches in cholestatic liver disease, with a particular focus on primary biliary cholangitis (PBC). Key episode timestamps: 0:00:00 – Guest intro & evolution of PBC therapy 0:07:34 – Redefining biochemical response & earlier assessment 0:16:26 – OCA withdrawal & positioning PPARs/fibrates 0:22:16 – Diagnosing AMA‑negative PBC 0:25:58 – Genetic cholestasis panels & PFIC spectrum 0:29:45 – Symptom burden, pruritus, & IBAT inhibitors 0:35:17 – Bone health & closing remarks","meta_description":"In this episode of Liver Lineup: Updates & Unfiltered Insights , host Nancy Reau, MD, sits down with Kris Kowdley, MD, to discuss evolving approaches…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2165,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/hcplive-podcasts-19526/episodes/liver-lineup-innovations-in-cholestatic-disease-management-with-kris-kowdley-md/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/hcplive-podcasts-19526/liver-lineup-innovations-in-cholestatic-disease-management-with-kris-kowdley-md.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}