{"podcast":{"title":"From Models to Medicine","slug":"from-models-to-medicine-7769799","podcast_index_feed_id":7769799,"rss_url":"https://anchor.fm/s/110164688/podcast/rss","website_url":"https://podcasters.spotify.com/pod/show/kami-think-tank","image_url":"https://d3t3ozftmdmh3i.cloudfront.net/staging/podcast_uploaded_nologo/45548626/45548626-1773273198170-a0661f37581aa.jpg","author":"KAMI Think Tank","episode_count":19,"summary":"At KAMI Think Tank, we love cutting through the AI hype to showcase where the technology actually stands and how to use it meaningfully within the life sciences. Now, we're bringing that same clarity with our community to a brand new podcast: From Models to Medicine. Every week, we sit down with a real practitioner in the life sciences, whether they're working in the lab, leading innovation at a biotech, or building tools to better serve scientists. We discuss how they cut through the hype of AI and practically leverage the tool in their scientific workflows. Glad to have you here.","last_synced_at":"2026-07-30T04:19:36.234491+00:00","page_url":"https://stenobird.com/podcast/from-models-to-medicine-7769799"},"episode":{"title":"Episode 18: Why Does mRNA Keep Breaking AI Models?","slug":"episode-18-why-does-mrna-keep-breaking-ai-models","published_at":"2026-07-29T14:37:00+00:00","page_url":"https://stenobird.com/podcast/from-models-to-medicine-7769799/episode-18-why-does-mrna-keep-breaking-ai-models","show_page_url":"https://stenobird.com/podcast/from-models-to-medicine-7769799","url":"https://podcasters.spotify.com/pod/show/kami-think-tank/episodes/Episode-18-Why-Does-mRNA-Keep-Breaking-AI-Models-e3mcg0n","audio_url":"https://anchor.fm/s/110164688/podcast/play/123141591/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-6-27%2F51845afb-f550-bc78-841f-c1a08fc61199.mp3","summary":"In this episode, we sit down with Chris Nelson , an mRNA scientist at nCode Bio whose career has taken him from building blood transfusion matching tests now used by the NHS, to cancer genomics at Personalis, to the frontier of mRNA sequence design. Chris breaks down why the untranslated regions of mRNA might actually change how we dose therapeutics, reduce side effects, and engineer cells inside the body entirely. Then we talk about why AI has conquered protein folding but keeps hitting a wall with mRNA. Chris walks us through the data problem, the cost problem, and the modeling choices nCode Bio is making that go against the grain of what most of the field is building. He's also candid about where the big model providers are letting biology down and which scrappy research groups he thinks are quietly building the tools that will actually matter.","meta_description":"In this episode, we sit down with Chris Nelson , an mRNA scientist at nCode Bio whose career has taken him from building blood transfusion matching tests…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2408,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/from-models-to-medicine-7769799/episodes/episode-18-why-does-mrna-keep-breaking-ai-models/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/from-models-to-medicine-7769799/episode-18-why-does-mrna-keep-breaking-ai-models.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}