{"podcast":{"title":"Free Radicals","slug":"free-radicals-7588534","podcast_index_feed_id":7588534,"rss_url":"https://anchor.fm/s/107b5162c/podcast/rss","website_url":"https://podcasters.spotify.com/pod/show/danielshur","image_url":"https://d3t3ozftmdmh3i.cloudfront.net/staging/podcast_uploaded_nologo/44142755/44142755-1763427468732-7a584148b3c73.jpg","author":"Daniel Shur and Eric Dai","episode_count":24,"summary":"Interviewing visionaries dedicated to giving humanity control over biology. All problems are solvable, including aging and death.","last_synced_at":"2026-06-24T00:19:52.263803+00:00","page_url":"https://stenobird.com/podcast/free-radicals-7588534"},"episode":{"title":"Finding genes at scale for age reversal - Shift Bio CEO Daniel Ives","slug":"finding-genes-at-scale-for-age-reversal-shift-bio-ceo-daniel-ives","published_at":"2026-02-03T14:38:01+00:00","page_url":"https://stenobird.com/podcast/free-radicals-7588534/finding-genes-at-scale-for-age-reversal-shift-bio-ceo-daniel-ives","show_page_url":"https://stenobird.com/podcast/free-radicals-7588534","url":"https://podcasters.spotify.com/pod/show/danielshur/episodes/Finding-genes-at-scale-for-age-reversal---Shift-Bio-CEO-Daniel-Ives-e3ej0vu","audio_url":"https://anchor.fm/s/107b5162c/podcast/play/114966974/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-1-3%2F417387741-44100-2-e634295edfd4d.mp3","summary":"Dr. Daniel Ives is the founder of Shift Bioscience. Shift has built a novel single-cell aging clock that has enabled them to run high-throughput screens to discover genes that regulate aging, with the goal of identifying a therapy to systemically reverse aging. We’ll dive deep into Shift’s latest work on SB000, a germline-expressed gene that rejuvenates cells without inducing pluripotency, and SB101, a pro-aging gene whose inhibition both reverses cellular age and prevents fibrosis, opening a clear path to clinical development. Daniel also shares his philosophy on why reversing aging might be easier than we think, the coming cultural shift when anti-aging drugs become mundane reality, and why he won't rest until we can double human lifespan.","meta_description":"Dr. Daniel Ives is the founder of Shift Bioscience. Shift has built a novel single-cell aging clock that has enabled them to run high-throughput screens t…","key_points":[],"chapters":[],"topics":[],"duration_seconds":4673,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/free-radicals-7588534/episodes/finding-genes-at-scale-for-age-reversal-shift-bio-ceo-daniel-ives/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/free-radicals-7588534/finding-genes-at-scale-for-age-reversal-shift-bio-ceo-daniel-ives.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}