{"podcast":{"title":"First Principles","slug":"first-principles-7708985","podcast_index_feed_id":7708985,"rss_url":"https://feeds.megaphone.fm/PODAGEN4765221373","website_url":null,"image_url":"https://megaphone.imgix.net/podcasts/06eebd2a-0779-11f1-826e-37926ac18342/image/fca7c8febd1441fc3b0d54084418b06d.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"Adrian Wells","episode_count":324,"summary":"First Principles isn't another business podcast recycling the same startup stories. Adrian Wells takes the fundamentals that actually matter and breaks them down like you're having coffee with the smartest professor you ever had. Wells spent twelve years teaching philosophy and critical thinking before ditching the lecture hall for the microphone. Turns out, the same principles that help you think clearly about ancient Greek ethics also work pretty well for modern business decisions. Who knew? Every episode strips away the latest trends and buzzwords to focus on the core ideas that don't change. How to actually evaluate evidence when everyone's throwing around statistics. Why most \"revolutionary\" business advice is just old wine in new bottles. The thinking patterns that separate smart decisions from lucky guesses. You won't get hyped-up success stories or flavor-of-the-month strategies. Instead, you'll learn how to think through problems the way philosophers have for centuries, applied to the stuff that matters in your work and life right now. Multiple new episodes drop daily, so there's always something fresh when you need it. Follow now if you're ready to think better, not just…","last_synced_at":"2026-07-23T16:19:48.696188+00:00","page_url":"https://stenobird.com/podcast/first-principles-7708985"},"episode":{"title":"No.1 Nitric Oxide Expert: The Anti-Aging Molecule Your Doctor Won't Tell You About","slug":"no-1-nitric-oxide-expert-the-anti-aging-molecule-your-doctor-won-t-tell-you-about","published_at":"2026-07-18T16:12:00+00:00","page_url":"https://stenobird.com/podcast/first-principles-7708985/no-1-nitric-oxide-expert-the-anti-aging-molecule-your-doctor-won-t-tell-you-about","show_page_url":"https://stenobird.com/podcast/first-principles-7708985","url":"https://traffic.megaphone.fm/PODAGEN2258668015.mp3?updated=1776258557","audio_url":"https://traffic.megaphone.fm/PODAGEN2258668015.mp3?updated=1776258557","summary":"What if I told you there's a molecule your body makes that could be the key to staying young, but your doctor probably never mentioned it? Adrian Wells sits down with the world's leading nitric oxide researcher to uncover why this Nobel Prize-winning discovery is being called the \"fountain of youth molecule\" hiding in plain sight. 🎯 What You'll Learn: • Why nitric oxide drops by 50% between ages 40-70 and what that means for your health • The simple beetroot trick that boosts plasma nitrate levels by 300% in under 3 hours • How the 1998 Nobel Prize discovery connects to why some people age gracefully while others don't • The endothelial function test that predicts longevity better than most medical screenings 👤 Perfect for: lifelong learners and anyone who wants to understand the science behind healthy aging without the marketing hype. 📍 Chapters: [00:00] Adrian introduces the anti-aging molecule doctors ignore [01:45] What nitric oxide actually does in your body [03:30] Why production crashes after 40 (and what to do about it) [06:15] The beetroot study that changed everything [08:45] Simple ways to measure your nitric oxide levels [11:00] Practical steps you can start today This isn't another supplement pitch or biohacking fad. It's hard science about a molecule that regulates blood flow, cellular energy, and tissue repair. The kind of foundational knowledge that helps you make better decisions about your health for decades to come. 🔔 Never miss an episode: Follow First Principles on Spotify or Apple Podcasts and turn on notifications. New episodes drop daily, your next breakthrough insight is one tap away. 🔍 Topics: nitric oxide, anti-aging, longevity science, cardiovascular health, Nobel Prize medicine Find all episodes at First Principles --------- Keywords: behav…","meta_description":"What if I told you there's a molecule your body makes that could be the key to staying young, but your doctor probably never mentioned it? Adrian Wells si…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1145,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/first-principles-7708985/episodes/no-1-nitric-oxide-expert-the-anti-aging-molecule-your-doctor-won-t-tell-you-about/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/first-principles-7708985/no-1-nitric-oxide-expert-the-anti-aging-molecule-your-doctor-won-t-tell-you-about.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}