{"podcast":{"title":"First Principles","slug":"first-principles-7708985","podcast_index_feed_id":7708985,"rss_url":"https://feeds.megaphone.fm/PODAGEN4765221373","website_url":null,"image_url":"https://megaphone.imgix.net/podcasts/06eebd2a-0779-11f1-826e-37926ac18342/image/fca7c8febd1441fc3b0d54084418b06d.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"Adrian Wells","episode_count":324,"summary":"First Principles isn't another business podcast recycling the same startup stories. Adrian Wells takes the fundamentals that actually matter and breaks them down like you're having coffee with the smartest professor you ever had. Wells spent twelve years teaching philosophy and critical thinking before ditching the lecture hall for the microphone. Turns out, the same principles that help you think clearly about ancient Greek ethics also work pretty well for modern business decisions. Who knew? Every episode strips away the latest trends and buzzwords to focus on the core ideas that don't change. How to actually evaluate evidence when everyone's throwing around statistics. Why most \"revolutionary\" business advice is just old wine in new bottles. The thinking patterns that separate smart decisions from lucky guesses. You won't get hyped-up success stories or flavor-of-the-month strategies. Instead, you'll learn how to think through problems the way philosophers have for centuries, applied to the stuff that matters in your work and life right now. Multiple new episodes drop daily, so there's always something fresh when you need it. Follow now if you're ready to think better, not just…","last_synced_at":"2026-07-23T16:19:48.696188+00:00","page_url":"https://stenobird.com/podcast/first-principles-7708985"},"episode":{"title":"I Tested 100,000 People's DNA: This Common Diet Will Kill You","slug":"i-tested-100-000-people-s-dna-this-common-diet-will-kill-you","published_at":"2026-07-23T02:24:00+00:00","page_url":"https://stenobird.com/podcast/first-principles-7708985/i-tested-100-000-people-s-dna-this-common-diet-will-kill-you","show_page_url":"https://stenobird.com/podcast/first-principles-7708985","url":"https://traffic.megaphone.fm/PODAGEN8210744056.mp3?updated=1776258331","audio_url":"https://traffic.megaphone.fm/PODAGEN8210744056.mp3?updated=1776258331","summary":"What if the diet advice you've been following could actually be killing you? Gary Brecka claims he's tested over 100,000 people's DNA and discovered something shocking about how our genes respond to different foods. In this episode, Adrian Wells breaks down Brecka's bold claims and separates the legitimate science from the marketing hype. 🎯 What You'll Learn: • Why the FDA doesn't regulate genetic nutrition testing (and what that means for you) • The real percentage your genetics actually influence your diet response (it's way lower than you think) • How to spot red flags in genetic testing companies making outrageous claims • What legitimate nutritional genetics can and cannot tell you about your health 👤 Perfect for: lifelong learners and anyone who's ever wondered if those expensive DNA diet tests are worth the money. 📍 Chapters: [00:00] Adrian Wells introduces Gary Brecka's DNA diet claims [02:15] The 100,000 DNA tests: impressive number or marketing trick? [04:30] What the FDA actually regulates in genetic testing [06:45] The 10-15% rule: how much genetics really matter for nutrition [09:00] Small effect sizes: why your genes influence but don't determine your diet [11:30] Red flags to watch for in genetic nutrition companies The truth about personalized nutrition based on your DNA is way more nuanced than most companies want you to believe. Brecka's claims sound revolutionary, but the actual science tells a different story. Your genetics do matter for nutrition, just not in the dramatic way these tests often promise. 🔔 Never miss an episode: Follow First Principles on Spotify or Apple Podcasts and turn on notifications. New episodes drop daily, your next favorite insight is one tap away. 🔍 Topics: DNA testing, personalized nutrition, Gary Brecka, genetic diet adv…","meta_description":"What if the diet advice you've been following could actually be killing you? Gary Brecka claims he's tested over 100,000 people's DNA and discovered somet…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1286,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/first-principles-7708985/episodes/i-tested-100-000-people-s-dna-this-common-diet-will-kill-you/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/first-principles-7708985/i-tested-100-000-people-s-dna-this-common-diet-will-kill-you.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}