{"podcast":{"title":"First Principles","slug":"first-principles-7708985","podcast_index_feed_id":7708985,"rss_url":"https://feeds.megaphone.fm/PODAGEN4765221373","website_url":null,"image_url":"https://megaphone.imgix.net/podcasts/06eebd2a-0779-11f1-826e-37926ac18342/image/fca7c8febd1441fc3b0d54084418b06d.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"Adrian Wells","episode_count":324,"summary":"First Principles isn't another business podcast recycling the same startup stories. Adrian Wells takes the fundamentals that actually matter and breaks them down like you're having coffee with the smartest professor you ever had. Wells spent twelve years teaching philosophy and critical thinking before ditching the lecture hall for the microphone. Turns out, the same principles that help you think clearly about ancient Greek ethics also work pretty well for modern business decisions. Who knew? Every episode strips away the latest trends and buzzwords to focus on the core ideas that don't change. How to actually evaluate evidence when everyone's throwing around statistics. Why most \"revolutionary\" business advice is just old wine in new bottles. The thinking patterns that separate smart decisions from lucky guesses. You won't get hyped-up success stories or flavor-of-the-month strategies. Instead, you'll learn how to think through problems the way philosophers have for centuries, applied to the stuff that matters in your work and life right now. Multiple new episodes drop daily, so there's always something fresh when you need it. Follow now if you're ready to think better, not just…","last_synced_at":"2026-07-23T16:19:48.696188+00:00","page_url":"https://stenobird.com/podcast/first-principles-7708985"},"episode":{"title":"Dr. Eisenberg: Your Age Is Damaging Your Future Kids (The Sperm Truth)","slug":"dr-eisenberg-your-age-is-damaging-your-future-kids-the-sperm-truth","published_at":"2026-07-22T19:30:00+00:00","page_url":"https://stenobird.com/podcast/first-principles-7708985/dr-eisenberg-your-age-is-damaging-your-future-kids-the-sperm-truth","show_page_url":"https://stenobird.com/podcast/first-principles-7708985","url":"https://traffic.megaphone.fm/PODAGEN9180545226.mp3?updated=1776258339","audio_url":"https://traffic.megaphone.fm/PODAGEN9180545226.mp3?updated=1776258339","summary":"Here's when you realize everything you thought about having kids was wrong. Men in their 40s aren't just \"mature\" fathers - they're passing along 60% more DNA damage to their children than guys in their 20s. Adrian Wells sits down with fertility expert Dr. Michael Eisenberg to unpack the uncomfortable truth about paternal age that most doctors won't tell you. 🎯 What You'll Learn: • Why autism risk jumps 28% for every 10 years dad gets older • The real reason sperm count has crashed 50% globally in four decades • How men over 45 double their kids' schizophrenia risk later in life • Which fertility myths are keeping couples from making informed decisions 👤 Perfect for: lifelong learners and anyone thinking about starting a family or understanding the science behind reproductive health. 📍 Chapters: [00:00] Adrian introduces the paternal age crisis nobody talks about [02:15] Dr. Eisenberg breaks down the DNA damage timeline [04:30] The autism connection that shocked researchers [06:45] Why sperm quality matters more than sperm count [08:20] Global fertility decline: environmental factors vs. age [10:30] Practical advice for future parents This isn't about scaring anyone out of having kids. It's about making decisions with actual data instead of outdated assumptions. Dr. Eisenberg has spent his career studying male fertility, and his findings will change how you think about family planning timelines. The conversation gets specific fast. We're talking real numbers, not vague warnings. When 40-year-old sperm carries genetic mutations at rates that would alarm any geneticist, that's information you need before making life-changing decisions. 🔔 Never miss an episode: Follow First Principles on Spotify or Apple Podcasts and turn on notifications. New episodes drop daily, your ne…","meta_description":"Here's when you realize everything you thought about having kids was wrong. Men in their 40s aren't just \"mature\" fathers - they're passing along 60% more…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1112,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/first-principles-7708985/episodes/dr-eisenberg-your-age-is-damaging-your-future-kids-the-sperm-truth/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/first-principles-7708985/dr-eisenberg-your-age-is-damaging-your-future-kids-the-sperm-truth.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}