{"podcast":{"title":"Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+","slug":"everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097","podcast_index_feed_id":72097,"rss_url":"https://feeds.megaphone.fm/CTH5015378255","website_url":"https://cynthiathurlow.com/podcast","image_url":"https://megaphone.imgix.net/podcasts/1d7d0888-c5c2-11eb-9609-eb0ddaa88f9d/image/e47b0ba3f061eba8ffa079c1196fdd6e.jpg?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"Cynthia Thurlow","episode_count":769,"summary":"Looking for the latest strategies for dealing with menopause, hormones and midlife health issues? You're in the right place! Cynthia Thurlow is a nurse practitioner, host of the Everyday Wellness podcast, author and international speaker, with over 15 million views for her second TEDx talk (Intermittent Fasting: Transformational Technique). With over 25 years experience in health and wellness, Cynthia is a globally recognized expert in perimenopause/menopause and intermittent fasting, and has been featured on ABC, FOX5, KTLA, CW, Medium, Entrepreneur, and The Megyn Kelly Show. Her mission is to help empower women to live their most optimal lives in perimenopause and beyond.","last_synced_at":"2026-09-24T06:20:47.420971+00:00","page_url":"https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097"},"episode":{"title":"BONUS: Spermidine and Autophagy with Leslie Kenny | Menopause, Perimenopause, Longevity","slug":"bonus-spermidine-and-autophagy-with-leslie-kenny-menopause-perimenopause-longevity","published_at":"2026-09-14T07:00:00+00:00","page_url":"https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/bonus-spermidine-and-autophagy-with-leslie-kenny-menopause-perimenopause-longevity","show_page_url":"https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097","url":"https://traffic.megaphone.fm/CTH9930413986.mp3","audio_url":"https://traffic.megaphone.fm/CTH9930413986.mp3","summary":"Welcome to the latest episode in our series of highly vetted companies I like to share with my Everyday Wellness community. Today, I’m delighted to connect with Leslie Kenny, Founder and CEO of Oxford Healthspan. After being diagnosed with multiple autoimmune conditions and being told she was unlikely to have any biological children, Leslie put her autoimmune conditions into remission through nutrition and lifestyle changes and later went on to conceive naturally at 43. Her personal experience led her into a research collaboration with Oxford immunologist Professor Katya Simon, where she was introduced to spermidine, a naturally occurring polyamine studied for its role in autophagy—our cells’ internal recycling and cleanup process. She later founded Oxford Healthspan to bring a whole-food Japan-sourced spermidine supplement, Primadine, to market. She also co-founded the non-profit Oxford Longevity Project alongside Oxford scientists to educate the public more broadly on healthspan research. In our conversation, we discuss self-advocacy, autoimmunity, infertility, and empowerment, exploring how modern life affects perimenopause and menopause, as well as spermidine research and its mechanisms of action. We discuss intermittent fasting, autophagy, mitophagy, gut health, food-based sources of spermidine, how our spermidine levels decrease with age, and why supplementation is truly beneficial. Leslie also shares feedback on how Primadine impacts memory, cognition, hair, skin, and nails; how clock genes and circadian biology work; and biological versus chronological age. Stay tuned for a truly fascinating conversation with Leslie Kenny- one you’ll most likely want to revisit more than once. IN THIS EPISODE, YOU WILL LEARN: The changes Leslie implemented after being diagnosed…","meta_description":"Welcome to the latest episode in our series of highly vetted companies I like to share with my Everyday Wellness community. Today, I’m delighted to connec…","key_points":[],"chapters":[],"topics":[],"duration_seconds":4514,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/episodes/bonus-spermidine-and-autophagy-with-leslie-kenny-menopause-perimenopause-longevity/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/everyday-wellness-midlife-hormones-menopause-and-science-for-women-35-72097/bonus-spermidine-and-autophagy-with-leslie-kenny-menopause-perimenopause-longevity.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}