{"podcast":{"title":"EP Edge Journal Watch: Cardiac Electrophysiology Research","slug":"ep-edge-journal-watch-7561379","podcast_index_feed_id":7561379,"rss_url":"https://feeds.transistor.fm/ep-edge-journal-watch","website_url":null,"image_url":"https://img.transistorcdn.com/KWuXQ6fPAArQRCgfrqrxfzQNWh_DnAU4t75wkubUSk4/rs:fill:0:0:1/w:1400/h:1400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9jMzFi/ZTYxOTI1M2U4NGRj/OGZmZjBhMDFlMjFm/NDQwMC5wbmc.jpg","author":"Niraj Sharma","episode_count":45,"summary":"Welcome to EP Edge Journal Watch, where cardiac electrophysiology meets evidence, precision, and perspective. Hosted by Dr. Niraj Sharma, this weekly podcast distills high-impact cardiovascular and Cardiac Electrophysiology and arrhythmia research into clear, clinically meaningful insights. Each episode goes beyond headlines and abstracts to uncover what new studies actually mean for patient care, decision-making, and the future of electrophysiology. What EP Edge Journal Watch stands for: Evidence-based practice Precision electrophysiology, arrhythmias analysis A forward-thinking, edge-driven approach to how we interpret and apply data in real-world clinical settings. Whether you’re an electrophysiologist, cardiologist, researcher, trainee, or allied health professional, EP Edge Journal Watch brings you the signal not the noise. Expect sharp summaries, thoughtful commentary, and practical takeaways designed for the busy clinician who wants to stay ahead of the curve","last_synced_at":"2026-09-14T18:19:31.787966+00:00","page_url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379"},"episode":{"title":"EP Edge™ Journal Watch: February 2026 Issue 12: AF Ablation “Success” Reframed: ADVENT-LTO 4-Year PFA Durability, 20-Year PVI Outcomes, Monitoring Rules, CIED Risks & PICM","slug":"ep-edge-journal-watch-february-2026-issue-12-af-ablation-success-reframed-advent-lto-4-year-pfa-durability-20-year-pvi-outcomes-monitoring-rules-cied-risks-picm","published_at":"2026-02-23T10:30:00+00:00","page_url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-february-2026-issue-12-af-ablation-success-reframed-advent-lto-4-year-pfa-durability-20-year-pvi-outcomes-monitoring-rules-cied-risks-picm","show_page_url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379","url":"https://share.transistor.fm/s/beb49808","audio_url":"https://media.transistor.fm/beb49808/56aed6e8.mp3","summary":"In this episode of EP Edge™ Journal Watch (Issue 12, February 2026) , Dr. Niraj Sharma breaks down a deceptively simple question in atrial fibrillation (AF) ablation: what does “success” actually mean—at 1 year, 4 years, and 20 years? We start with ADVENT-LTO , the long-term extension of the randomized ADVENT trial, examining 4-year outcomes of pulse field ablation (PFA) vs thermal ablation —and why redo ablation and hospital-based interventions may matter more than a single headline p-value. Next, we zoom way out with a 20-year pulmonary vein isolation (PVI) cohort , showing how AF behaves like a progressive atrial cardiomyopathy over decades—and why very late recurrences may occur even when PV isolation remains durable. Then we tackle the “quiet drivers” of trial results: monitoring intensity, the 30-second recurrence rule, blanking periods, and AF burden —the design choices that can make technologies look better (or worse) without changing biology. Finally, two practical, real-world segments: ablation in patients with pacemakers/ICDs (MAUDE signal patterns, including resets and generator issues) and pacing-induced cardiomyopathy (PICM) in the leadless era (leadless vs transvenous RV pacing) . Full written issue (with references) is on Substack: epedge.substack.com and on LinkedIn Newsletter EP Edge Journal Watch","meta_description":"In this episode of EP Edge™ Journal Watch (Issue 12, February 2026) , Dr. Niraj Sharma breaks down a deceptively simple question in atrial fibrillation (A…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1488,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/ep-edge-journal-watch-7561379/episodes/ep-edge-journal-watch-february-2026-issue-12-af-ablation-success-reframed-advent-lto-4-year-pfa-durability-20-year-pvi-outcomes-monitoring-rules-cied-risks-picm/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-february-2026-issue-12-af-ablation-success-reframed-advent-lto-4-year-pfa-durability-20-year-pvi-outcomes-monitoring-rules-cied-risks-picm.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}