{"podcast":{"title":"EP Edge Journal Watch: Cardiac Electrophysiology Research","slug":"ep-edge-journal-watch-7561379","podcast_index_feed_id":7561379,"rss_url":"https://feeds.transistor.fm/ep-edge-journal-watch","website_url":null,"image_url":"https://img.transistorcdn.com/KWuXQ6fPAArQRCgfrqrxfzQNWh_DnAU4t75wkubUSk4/rs:fill:0:0:1/w:1400/h:1400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9jMzFi/ZTYxOTI1M2U4NGRj/OGZmZjBhMDFlMjFm/NDQwMC5wbmc.jpg","author":"Niraj Sharma","episode_count":45,"summary":"Welcome to EP Edge Journal Watch, where cardiac electrophysiology meets evidence, precision, and perspective. Hosted by Dr. Niraj Sharma, this weekly podcast distills high-impact cardiovascular and Cardiac Electrophysiology and arrhythmia research into clear, clinically meaningful insights. Each episode goes beyond headlines and abstracts to uncover what new studies actually mean for patient care, decision-making, and the future of electrophysiology. What EP Edge Journal Watch stands for: Evidence-based practice Precision electrophysiology, arrhythmias analysis A forward-thinking, edge-driven approach to how we interpret and apply data in real-world clinical settings. Whether you’re an electrophysiologist, cardiologist, researcher, trainee, or allied health professional, EP Edge Journal Watch brings you the signal not the noise. Expect sharp summaries, thoughtful commentary, and practical takeaways designed for the busy clinician who wants to stay ahead of the curve","last_synced_at":"2026-09-14T18:19:31.787966+00:00","page_url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379"},"episode":{"title":"EP Edge Journal Watch #14 (March 2026):  AF Ablation at the Extremes: Octogenarians, HFrEF PVI-Only, LAAC, PFA Hemolysis/AKI & Redo Timing","slug":"ep-edge-journal-watch-14-march-2026-af-ablation-at-the-extremes-octogenarians-hfref-pvi-only-laac-pfa-hemolysis-aki-redo-timing","published_at":"2026-03-09T09:30:00+00:00","page_url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-14-march-2026-af-ablation-at-the-extremes-octogenarians-hfref-pvi-only-laac-pfa-hemolysis-aki-redo-timing","show_page_url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379","url":"https://share.transistor.fm/s/7d54f910","audio_url":"https://media.transistor.fm/7d54f910/2b4dfe8e.mp3","summary":"In EP Edge Journal Watch Issue 14 (March 2026) , Dr. Niraj Sharma breaks down the most clinically “edge-case” decisions in contemporary electrophysiology—where ablation strategy, stroke prevention, and safety monitoring collide. This episode covers: AF ablation in octogenarians (REHEALTH AF): why the signal may be less about short-term hard outcomes and more about symptoms, function, and patient-centered endpoints. Heart failure + AF (POLAR-HF): the case for a standardized PVI-only approach in HFrEF—and when simplicity is the point. LAAC after ablation (OPTION subanalysis): whether left atrial appendage closure changes AF recurrence (and why rhythm success ≠ stroke immunity). Severe spontaneous echo contrast before LAAC (OCEAN-LAAC): when “smoke” is a high-risk biology phenotype that should change surveillance and post-device antithrombotic strategy. Multimorbidity and PVI: what long-term recurrence really looks like in high comorbidity-burden patients—and how to reset goals toward AF burden and symptoms. Pulsed field ablation safety: hemolysis markers (haptoglobin depletion) , AKI risk under routine hydration , and who needs tighter post-procedure monitoring (Farapulse vs PulseSelect). Redo ablation timing: evidence that earlier repeat ablation after recurrence may improve rhythm and quality-of-life outcomes. Plus: PACED score for LVEF recovery after AF ablation, LBBAP upgrades for pacing-induced cardiomyopathy, and a cardiology bonus trial ( APERITIF ) on LV thrombus prevention after anterior STEMI. References and visuals are available with the newsletter on LinkedIn and on Substack (epedge.substack.com) .","meta_description":"In EP Edge Journal Watch Issue 14 (March 2026) , Dr. Niraj Sharma breaks down the most clinically “edge-case” decisions in contemporary electrophysiology—…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2006,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/ep-edge-journal-watch-7561379/episodes/ep-edge-journal-watch-14-march-2026-af-ablation-at-the-extremes-octogenarians-hfref-pvi-only-laac-pfa-hemolysis-aki-redo-timing/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/ep-edge-journal-watch-7561379/ep-edge-journal-watch-14-march-2026-af-ablation-at-the-extremes-octogenarians-hfref-pvi-only-laac-pfa-hemolysis-aki-redo-timing.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}