{"podcast":{"title":"Dr. John Campbell","slug":"dr-john-campbell-7851784","podcast_index_feed_id":7851784,"rss_url":"https://feeds.megaphone.fm/VG9554039150","website_url":null,"image_url":"https://megaphone.imgix.net/podcasts/7a133470-32e4-11f1-ae26-ef5a830a5f06/image/aacd596ff9b51467520b0238cfcd1c87.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"Campbellteaching","episode_count":658,"summary":"Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider","last_synced_at":"2026-09-22T06:22:02.195523+00:00","page_url":"https://stenobird.com/podcast/dr-john-campbell-7851784"},"episode":{"title":"% lethal rate SARS virus","slug":"lethal-rate-sars-virus","published_at":"2026-09-14T03:00:00+00:00","page_url":"https://stenobird.com/podcast/dr-john-campbell-7851784/lethal-rate-sars-virus","show_page_url":"https://stenobird.com/podcast/dr-john-campbell-7851784","url":"https://traffic.megaphone.fm/VG8080793350.mp3?updated=1778683382","audio_url":"https://traffic.megaphone.fm/VG8080793350.mp3?updated=1778683382","summary":"Virus being experimented on in China. https://www.researchgate.net/publication/377199018_Lethal_Infection_of_Human_ACE2-Transgenic_Mice_Caused_by_SARS-CoV-2-related_Pangolin_Coronavirus_GX_P2Vshort_3UTR https://www.biorxiv.org/content/10.1101/2024.01.03.574008v1.full.pdf https://www.theepochtimes.com/health/chinese-scientists-reveal-experiments-with-virus-100-percent-fatal-to-mice-5560854?utm_source=atcn&utm_content=hw1016multicomp&utm_medium=email&utm_campaign=atc&utm_term=hws1comp SARS-CoV-2-related pangolin coronavirus GX_P2V, can cause 100% mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain infection. Paper Authors Beijing Advanced Innovation Center Beijing University of Chemical Technology, The Fifth Medical Center of PLA General Hospital, Beijing, China. Medical School, Nanjing University, China (including a doctor trained by the Chinese military, Yigang Tong) Purpose of study Assessed virus pathogenicity Risk 100% IFR underscores a spillover risk of GX_P2V into humans, and provides a unique model for understanding the pathogenic mechanisms of SARS-CoV-2-related viruses. Details GX_P2V isolate was actually a cell culture-adapted mutant In this study, we cloned this mutant This is not a wild type virus It is possible that GX_P2V C7 has undergone a virulence-enhancing mutation. GX_P2V is capable of rapid mutation rates. High viral loads detected in both lung and brain tissues. Surprisingly, all the mice that were infected with the live virus succumbed to the infection within 7-8 days post-inoculation, Resulted in 100% mortality in the hACE2 mice. Clinical features Weight loss, Piloerection, hunched posture, sluggish movements, and their eyes turned white. Significant amounts of viral RNA in the brain, lung, turbina…","meta_description":"Virus being experimented on in China. https://www.researchgate.net/publication/377199018_Lethal_Infection_of_Human_ACE2-Transgenic_Mice_Caused_by_SARS-CoV…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1087,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/dr-john-campbell-7851784/episodes/lethal-rate-sars-virus/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/dr-john-campbell-7851784/lethal-rate-sars-virus.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}