{"podcast":{"title":"Diabetic Foot Files","slug":"diabetic-foot-files-7302870","podcast_index_feed_id":7302870,"rss_url":"https://feed.podbean.com/gdhutche/feed.xml","website_url":"https://gdhutche.podbean.com","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/20507692/son_halim8f236.jpg","author":"Diabetic Foot Files","episode_count":349,"summary":"Welcome to the Diabetic Foot Files Podcast—the show where we uncover the real stories, latest research, and essential tips to help prevent diabetic foot complications. I’m Dr. G aka Dr. Gabrielle Hutcheson Donaldson and as a podiatrist and wound care specialist . I’m here to educate, empower, and guide you through the world of diabetic foot care. From wound healing to amputation prevention, we’ll break down the facts, bust the myths, and share life-saving strategies. Whether you’re a patient, caregiver, or healthcare professional, this podcast is your go-to resource for healthier feet and a better quality of life. So let’s dive in—because when it comes to diabetes, every step matters!”","last_synced_at":"2026-07-28T00:18:44.165291+00:00","page_url":"https://stenobird.com/podcast/diabetic-foot-files-7302870"},"episode":{"title":"The Oxygen Thermostat: HIF‑1α and Diabetic Wound Healing- The Wound Healing Protein You Probably Never Heard Of","slug":"the-oxygen-thermostat-hif-1-and-diabetic-wound-healing-the-wound-healing-protein-you-probably-never-heard-of","published_at":"2026-07-11T07:34:42+00:00","page_url":"https://stenobird.com/podcast/diabetic-foot-files-7302870/the-oxygen-thermostat-hif-1-and-diabetic-wound-healing-the-wound-healing-protein-you-probably-never-heard-of","show_page_url":"https://stenobird.com/podcast/diabetic-foot-files-7302870","url":"https://gdhutche.podbean.com/e/the-oxygen-thermostat-hif%e2%80%911%ce%b1-and-diabetic-wound-healing/","audio_url":"https://mcdn.podbean.com/mf/web/yssiefkg2aucyb2s/The_Oxygen_Switch-_How_HIF_1alpha_changed_medicine_and_why_it_fails_in_diabetic_foot_ulcers_-a84rbw-Optimized.mp3","summary":"Dr. G explains how hypoxia‑inducible factor 1 alpha (HIF‑1α) acts as the cell's oxygen sensor and coordinator of wound repair, why diabetes disrupts its signaling, and how that impairment stalls healing in diabetic foot ulcers.The episode summarizes how researchers measure HIF‑1α, and reviews emerging treatments—HIF stabilizers, gene/RNA therapies, stem cells, engineered scaffolds, and oxygen‑releasing biomaterials—that aim to restore molecular healing pathways and improve limb salvage.","meta_description":"Dr. G explains how hypoxia‑inducible factor 1 alpha (HIF‑1α) acts as the cell's oxygen sensor and coordinator of wound repair, why diabetes disrupts its s…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1326,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/diabetic-foot-files-7302870/episodes/the-oxygen-thermostat-hif-1-and-diabetic-wound-healing-the-wound-healing-protein-you-probably-never-heard-of/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/diabetic-foot-files-7302870/the-oxygen-thermostat-hif-1-and-diabetic-wound-healing-the-wound-healing-protein-you-probably-never-heard-of.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}