{"podcast":{"title":"Data in Biotech","slug":"data-in-biotech-6628050","podcast_index_feed_id":6628050,"rss_url":"https://feed.pod.co/data-in-biotech","website_url":"https://www.corrdyn.com/","image_url":"https://images.pod.co/0up9NpIiXg38dg9ONujjEbhtOuwAOa32iObZVZ8ridQ/resize:fill:1500:1500/plain/artwork/9bd88ed6-6c74-4788-924c-56be77376f84/data-in-biotech.jpg","author":"CorrDyn","episode_count":77,"summary":"Data in Biotech is a fortnightly podcast exploring how companies leverage data to drive innovation in life sciences. Every two weeks, Ross Katz, Principal and Data Science Lead at CorrDyn, sits down with an expert from the world of biotechnology to understand how they use data science to solve technical challenges, streamline operations, and further innovation in their business. You can learn more about CorrDyn - an enterprise data specialist that enables excellent companies to make smarter strategic decisions - at www.corrdyn.com","last_synced_at":"2026-09-03T06:17:20.333193+00:00","page_url":"https://stenobird.com/podcast/data-in-biotech-6628050"},"episode":{"title":"Beyond Language: Why Drug Discovery Needs Physical AI, Not Just Large Language Models","slug":"beyond-language-why-drug-discovery-needs-physical-ai-not-just-large-language-models","published_at":"2026-07-20T16:33:10+00:00","page_url":"https://stenobird.com/podcast/data-in-biotech-6628050/beyond-language-why-drug-discovery-needs-physical-ai-not-just-large-language-models","show_page_url":"https://stenobird.com/podcast/data-in-biotech-6628050","url":"https://pod.co/data-in-biotech/beyond-language-why-drug-discovery-needs-physical-ai-not-just-large-language-models","audio_url":"https://downloads.pod.co/5fac40cd-043b-485f-838d-c63fa01ae1b2/5eff22ea-5ddf-4816-8605-d41b7b180fd7.mp3","summary":"In this episode of Data in Biotech, host Ross Katz sits down with Woody Sherman, Founder and Chief Innovation Officer at PsiThera, for a conversation on why AI can transform drug discovery's paperwork and code while barely touching the hardest part of the problem: the molecules themselves. Woody's career runs through physical chemistry at MIT; over a decade at Schrödinger building tools the industry still relies on; founding Silicon Therapeutics (where his team took a small molecule STING agonist from concept to clinic in roughly three years); scaling that platform after Roivant's acquisition; and now leading PsiThera's effort to build oral small molecules for immunology targets that today are only reachable with injectable biologics. The conversation digs into why large language models excel at automation, coding, and regulatory writing but hit a wall when the task is predicting how a molecule behaves, what \"physical AI\" actually means as a category distinct from both LLMs and traditional physics-based simulation, and why representing molecules as quantum mechanical objects rather than text strings or 2D graphs changes what's predictable. Woody also walks through the STING program in detail, why the field's excitement over fast co-folding models like Boltz needs a strong dose of skepticism, and what it takes to build a database and team culture where chemists, biologists, and data scientists can actually understand each other. What you'll learn in this episode: >> Why the contradiction of \"AI is transforming drug discovery\" and \"drugs still take a decade and billions of dollars\" can both be true at once. >> How Silicon Therapeutics engineered a small molecule STING agonist to dimerize itself through a quantum mechanical interaction that had never been desi…","meta_description":"In this episode of Data in Biotech, host Ross Katz sits down with Woody Sherman, Founder and Chief Innovation Officer at PsiThera, for a conversation on w…","key_points":[],"chapters":[],"topics":[],"duration_seconds":3487,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/data-in-biotech-6628050/episodes/beyond-language-why-drug-discovery-needs-physical-ai-not-just-large-language-models/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/data-in-biotech-6628050/beyond-language-why-drug-discovery-needs-physical-ai-not-just-large-language-models.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}