{"podcast":{"title":"Core IM | Internal Medicine Podcast","slug":"core-im-internal-medicine-podcast-60389","podcast_index_feed_id":60389,"rss_url":"https://feeds.redcircle.com/2c03e755-c428-4b8e-9150-95ef1ed2492b","website_url":"https://redcircle.com/shows/core-im-internal-medicine-podcast","image_url":"https://media.redcircle.com/images/2025/6/13/2/b2137ab0-0bbb-43a6-aaaa-b4b07adec3de_fcdc-ce25-48d2-986c-b209f60d7ebb_496745-915727.jpg","author":"Core IM Team","episode_count":217,"summary":"Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges","last_synced_at":"2026-06-10T20:19:29.041629+00:00","page_url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389"},"episode":{"title":"#202 Dementia Part 2: Gray Matters Segment","slug":"202-dementia-part-2-gray-matters-segment","published_at":"2026-03-12T08:22:24+00:00","page_url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389/202-dementia-part-2-gray-matters-segment","show_page_url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389","url":"https://www.coreimpodcast.com/2026/03/12/dementia-part-2-gray-matters-segment/","audio_url":"https://pscrb.fm/rss/p/audio2.redcircle.com/episodes/3ff397d6-8f21-42cf-9368-c2780a0fd4c3/stream.mp3","summary":"Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help . In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them. • Do cholinesterase inhibitors really work? • What should clinicians know about lecanemab and donanemab before referring patients? • How much benefit should we expect and for how long? • When should you deprescribe dementia medications ? 🔹 Sponsor: Caraway’s cookware set is a favorite for a reason. For 10% off, go to Carawayhome.com/ CoreIM or use code CoreIM at checkout. 🔹 Transcript and Shownotes 02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia? 09:41 | Deep Dive 2: Prescribing medications for cognitive decline 29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline 35:46 | Deep Dive 4: Planning for an uncertain future Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Advertising Inquiries: https://redcircle.com/brands Privacy & Opt-Out: https://redcircle.com/privacy","meta_description":"Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help . In this episode we break down donepezil,…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2836,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/core-im-internal-medicine-podcast-60389/episodes/202-dementia-part-2-gray-matters-segment/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389/202-dementia-part-2-gray-matters-segment.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}