{"podcast":{"title":"Core IM | Internal Medicine Podcast","slug":"core-im-internal-medicine-podcast-60389","podcast_index_feed_id":60389,"rss_url":"https://feeds.redcircle.com/2c03e755-c428-4b8e-9150-95ef1ed2492b","website_url":"https://redcircle.com/shows/core-im-internal-medicine-podcast","image_url":"https://media.redcircle.com/images/2025/6/13/2/b2137ab0-0bbb-43a6-aaaa-b4b07adec3de_fcdc-ce25-48d2-986c-b209f60d7ebb_496745-915727.jpg","author":"Core IM Team","episode_count":218,"summary":"Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges","last_synced_at":"2026-06-17T20:18:12.014085+00:00","page_url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389"},"episode":{"title":"#189 Bisphosphonates and Fracture Prevention Trial: Beyond Journal Club with NEJM Group","slug":"189-bisphosphonates-and-fracture-prevention-trial-beyond-journal-club-with-nejm-group","published_at":"2025-10-01T08:45:43+00:00","page_url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389/189-bisphosphonates-and-fracture-prevention-trial-beyond-journal-club-with-nejm-group","show_page_url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389","url":"https://www.coreimpodcast.com/2025/10/01/bones-and-bisphosphonates-bjc/","audio_url":"https://pscrb.fm/rss/p/audio2.redcircle.com/episodes/cf5dfaff-da82-45a3-957d-5f4b046f721c/stream.mp3","summary":"Who’s really at risk for fractures, and how should we be treating them? Most fragility fractures occur in patients without osteoporosis. Should we rethink who gets treated? And could just one or two IV infusions (spread years apart) of zoledronate prevent fractures for years? Have the concerns about bisphosphonates been overblown? Find out all the nuances on this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group. 🔹 Sponsor : Oakstone CME Use the code \"CORE25\" for 25% off: https://www.coreimpodcast.com/MKSAP 🔹 Transcript & Show Notes Timestamps: (00:59) | Diagnosing Osteoporosis and Hidden Fracture Risk (05:38) | Evolution of Bisphosphonate Use in Osteoporosis Treatment (07:51) | Current Use of Bisphosphonates: Benefits, Risks, and Side Effects (10:31) | Exploring Non-Bisphosphonate Options for Fracture Prevention (11:44) | Teriparatide and Alternative Osteoporosis Medications (14:53) | Inside the Latest Bisphosphonate Clinical Trial (18:07) | Key Findings from the Zoledronate Fracture Prevention Study (22:38) | Public Health Impact of Fracture Prevention Strategies (24:24) | Final Takeaways and Expert Perspectives on Osteoporosis Care Tags: CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Osteoporosis, Fragility Fractures, Zoledronate, Bone Health Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com * Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com * Check out Quince for high-quality clothes with affordable pricing and use code quince.com…","meta_description":"Who’s really at risk for fractures, and how should we be treating them? Most fragility fractures occur in patients without osteoporosis. Should we rethink…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1850,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/core-im-internal-medicine-podcast-60389/episodes/189-bisphosphonates-and-fracture-prevention-trial-beyond-journal-club-with-nejm-group/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/core-im-internal-medicine-podcast-60389/189-bisphosphonates-and-fracture-prevention-trial-beyond-journal-club-with-nejm-group.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}