{"podcast":{"title":"Continuum Audio","slug":"continuum-audio-6777185","podcast_index_feed_id":6777185,"rss_url":"https://feeds.libsyn.com/498048/rss","website_url":"https://continuumjournal.com","image_url":"https://static.libsyn.com/p/assets/c/6/6/5/c665c958d5ba721de5bbc093207a2619/ContinuumAudio_Icon_RGB.jpg","author":"American Academy of Neurology","episode_count":128,"summary":"Continuum Audio features conversations with the guest editors and authors of Continuum: Lifelong Learning in Neurology, the premier topic-based neurology clinical review and CME journal from the American Academy of Neurology. AAN members can earn CME for listening to interviews for review articles and completing the evaluation on the AAN's Online Learning Center.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/continuum-audio-6777185"},"episode":{"title":"Adult-Onset Leukodystrophies Mimicking Multiple Sclerosis With Dr. Roberta La Piana","slug":"adult-onset-leukodystrophies-mimicking-multiple-sclerosis-with-dr-roberta-la-piana","published_at":"2026-04-15T10:00:00+00:00","page_url":"https://stenobird.com/podcast/continuum-audio-6777185/adult-onset-leukodystrophies-mimicking-multiple-sclerosis-with-dr-roberta-la-piana","show_page_url":"https://stenobird.com/podcast/continuum-audio-6777185","url":"https://continuumjournal.libsyn.com/adult-onset-leukodystrophies-mimicking-multiple-sclerosis-with-dr-roberta-la-piana","audio_url":"https://traffic.libsyn.com/secure/continuumjournal/CA2026-MS-05-LaPiana_final_edit.mp3?dest-id=4262328","summary":"Adult‑onset leukodystrophies, though rare, can closely mimic MS on both clinical presentation and neuroimaging, posing a significant diagnostic challenge. This episode highlights key clinical and radiologic red flags that can help distinguish these disorders from MS, preventing misdiagnosis and avoiding inappropriate treatment while enabling timely genetic counseling and targeted therapies. In this episode, Teshamae Monteith, MD, FAAN, speaks with Roberta La Piana, MD, PhD, coauthor of the article \"Adult-Onset Leukodystrophies Mimicking Multiple Sclerosis\" in the Continuum ® April 2026 Multiple Sclerosis and Related Disorders issue. Dr. Monteith is the associate editor of Continuum® Audio and an associate professor of clinical neurology at the University of Miami Miller School of Medicine in Miami, Florida. Dr. La Piana is an associate professor in the Department of Neurology and Neurosurgery at the Montreal Neurological Institute, McGill University, and an associate member of the Department of Diagnostic Radiology at McGill University in Montreal, Quebec, Canada. Additional Resources Read the article: Adult-Onset Leukodystrophies Mimicking Multiple Sclerosis Subscribe to Continuum® : shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @headacheMD Full episode transcript available here Dr Monteith: You just saw a patient in clinic. And you're clear, the diagnosis is multiple sclerosis. Not everything fits, but it kind of looks like multiple sclerosis. You see the patient back years later. There'…","meta_description":"Adult‑onset leukodystrophies, though rare, can closely mimic MS on both clinical presentation and neuroimaging, posing a significant diagnostic challenge.…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1377,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/continuum-audio-6777185/episodes/adult-onset-leukodystrophies-mimicking-multiple-sclerosis-with-dr-roberta-la-piana/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/continuum-audio-6777185/adult-onset-leukodystrophies-mimicking-multiple-sclerosis-with-dr-roberta-la-piana.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}