{"podcast":{"title":"Blood Podcast","slug":"blood-podcast-664776","podcast_index_feed_id":664776,"rss_url":"https://feeds.transistor.fm/blood-podcast","website_url":null,"image_url":"https://img.transistorcdn.com/WlMZsA1edpS0qEIavlrh9KLfCFShKE7FTJxZLlZsByw/rs:fill:0:0:1/w:1400/h:1400/q:60/mb:500000/aHR0cHM6Ly9pbWct/dXBsb2FkLXByb2R1/Y3Rpb24udHJhbnNp/c3Rvci5mbS9kY2Q4/YzJhZmMwODBjOWRi/YTNhN2Y1NWJkMzMw/NTBjZi5qcGc.jpg","author":"American Society of Hematology","episode_count":388,"summary":"The Blood Podcast summarizes content recently published in Blood, the most cited peer-reviewed publication in the field of hematology.","last_synced_at":"2026-07-17T04:20:44.828596+00:00","page_url":"https://stenobird.com/podcast/blood-podcast-664776"},"episode":{"title":"PETAL Consortium Survival Prognosticators and How Inflammation Impacts Hematopoiesis","slug":"petal-consortium-survival-prognosticators-and-how-inflammation-impacts-hematopoiesis","published_at":"2026-03-05T17:00:00+00:00","page_url":"https://stenobird.com/podcast/blood-podcast-664776/petal-consortium-survival-prognosticators-and-how-inflammation-impacts-hematopoiesis","show_page_url":"https://stenobird.com/podcast/blood-podcast-664776","url":"https://share.transistor.fm/s/65259fd5","audio_url":"https://prfx.byspotify.com/e/media.transistor.fm/65259fd5/7a73e32c.mp3","summary":"In this week's episode, Blood associate editor Dr. Laura Michaelis interviews Drs. Mark Sorial and Emmanuelle Passegue on their articles published in volume 147 issue 7 of Blood . Dr. Sorial discusses \" Early time to relapse as a survival prognosticator in nodal mature T-cell lymphomas: results from the PETAL consortium \" where he and his team evaluated the prognostic significance of early relapse in a large retrospective cohort. They report a time to relapse of <12 months as a strong predictive factor independent of the prognostic index for T-cell lymphoma and histology, with results validated in 2 independent cohorts. Dr. Emmanuelle Passegue discusses \" Inflammation perturbs hematopoiesis by remodeling specific compartments of the bone marrow niche \". Using a combination of single-cell RNA sequencing profiling and flow cytometry, the team characterized the bone marrow niche compartments in mice subjected to inflammation. They show that inter-feron-mediated inflammation preferentially targets central marrow leptin receptor–expressing mesenchymal cells, triggering cytokine release that affects monocyte dynamics in the bone marrow microenvironment.","meta_description":"In this week's episode, Blood associate editor Dr. Laura Michaelis interviews Drs. Mark Sorial and Emmanuelle Passegue on their articles published in volu…","key_points":[],"chapters":[],"topics":[],"duration_seconds":780,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/blood-podcast-664776/episodes/petal-consortium-survival-prognosticators-and-how-inflammation-impacts-hematopoiesis/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/blood-podcast-664776/petal-consortium-survival-prognosticators-and-how-inflammation-impacts-hematopoiesis.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}