{"podcast":{"title":"BioTalk Unzipped","slug":"biotalk-unzipped-6702602","podcast_index_feed_id":6702602,"rss_url":"https://feeds.captivate.fm/biotalk-unzipped/","website_url":"https://www.biotalkunzipped.com","image_url":"https://artwork.captivate.fm/bc8c17ac-b08b-4ac4-b89d-c3f29318523c/updated-BioTalk-Logo.png","author":"Gregory Austin","episode_count":46,"summary":"BioTalk Unzipped, hosted by Gregory Austin and Dr. Chad Briscoe, unzips the stories behind medical progress through candid, intelligent, and often entertaining conversations with leaders across biotechnology, pharmaceuticals, medical technology, clinical research, bioanalysis, and drug development. Each episode explores the science, strategy, setbacks, breakthroughs, and human stories shaping the future of medicine. From first-in-human trials and biomarkers to oncology, rare disease, AI, regulatory strategy, and emerging therapeutic technologies, BioTalk Unzipped makes complex life science topics engaging, accessible, and relevant. The show feels like the conversation you would want to overhear after a great scientific conference: thoughtful, unscripted, curious, and grounded in real-world experience. We bring listeners inside the decisions, discoveries, and personal journeys behind the therapies and technologies that may one day reduce suffering and improve lives.","last_synced_at":"2026-09-11T10:23:01.173868+00:00","page_url":"https://stenobird.com/podcast/biotalk-unzipped-6702602"},"episode":{"title":"Do Clinical Trials Take Too Much Blood? Patient-Centric Sampling with Joleen White","slug":"do-clinical-trials-take-too-much-blood-patient-centric-sampling-with-joleen-white","published_at":"2026-09-11T02:30:00+00:00","page_url":"https://stenobird.com/podcast/biotalk-unzipped-6702602/do-clinical-trials-take-too-much-blood-patient-centric-sampling-with-joleen-white","show_page_url":"https://stenobird.com/podcast/biotalk-unzipped-6702602","url":"https://biotalk-unzipped.captivate.fm/episode/patient-centric-sampling-less-blood-better-trials","audio_url":"https://episodes.captivate.fm/episode/00da95bb-4f74-43d7-a382-e94a8262c407.mp3","summary":"Clinical trials often collect far more blood than an assay actually needs. Dr. Joleen White asks a more disciplined question: What information is required to make a sound decision, and how little sample can be collected without compromising that decision? In this episode of BioTalk Unzipped, recorded at the 2026 AAPS National Biotechnology Conference in San Diego, Dr. Chad Briscoe sits down with Joleen to explore patient-centric sampling, dried blood microsampling, global bioanalytical capacity, and the values behind better drug development. Joleen traces her path from a childhood friendship with someone living with cystic fibrosis to a career spanning BioMarin, BMS, Biogen, EMD Serono, the Gates Medical Research Institute, and BioData Solutions. She explains why bioanalysis became her way to help patients, why she eventually moved beyond the bench, and how global health work changed the way she thinks about laboratory infrastructure and clinical-trial design. The conversation then turns practical. Joleen defines patient-centric sampling, describes the Mitra dried blood collection device, and discusses a first-in-human RSV monoclonal antibody study in which paired dried-blood and serum samples led to aligned PK conclusions. She and Chad examine regulatory acceptance, remote collection, pediatric sampling, local laboratory capacity in African countries, scientific inclusion, career choices, AI, mass-spectrometry sensitivity, and whether long-standing sample-volume and stability expectations still serve patients. Sponsors TruTechnologies provides live clinical trial execution and oversight through point-of-care data capture. Learn more: https://trutechnologies.ai/ Leucentra provides specialized IT consulting and services for life sciences and healthcare. Learn more: http…","meta_description":"Clinical trials often collect far more blood than an assay actually needs. Dr. Joleen White asks a more disciplined question: What information is required…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2893,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/biotalk-unzipped-6702602/episodes/do-clinical-trials-take-too-much-blood-patient-centric-sampling-with-joleen-white/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/biotalk-unzipped-6702602/do-clinical-trials-take-too-much-blood-patient-centric-sampling-with-joleen-white.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}