{"podcast":{"title":"Biohacking Beauty: The Anti-Aging Skincare Podcast","slug":"biohacking-beauty-the-anti-aging-skincare-podcast-1375977","podcast_index_feed_id":1375977,"rss_url":"https://feeds.captivate.fm/biohacking-beauty/","website_url":"HTTPS://www.younggoose.com","image_url":"https://artwork.captivate.fm/298ca83b-8d04-48e9-9f13-64ac81e5b188/l62-_tnpsPe0KH5sj9Zklzmu.jpg","author":"Young Goose","episode_count":270,"summary":"Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond \"single-molecule\" trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ. We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.","last_synced_at":"2026-09-16T16:20:58.251623+00:00","page_url":"https://stenobird.com/podcast/biohacking-beauty-the-anti-aging-skincare-podcast-1375977"},"episode":{"title":"Chris Mirabile: Why One Ingredient Will Never Stop You From Aging (And What Actually Does)","slug":"chris-mirabile-why-one-ingredient-will-never-stop-you-from-aging-and-what-actually-does","published_at":"2026-05-13T08:00:00+00:00","page_url":"https://stenobird.com/podcast/biohacking-beauty-the-anti-aging-skincare-podcast-1375977/chris-mirabile-why-one-ingredient-will-never-stop-you-from-aging-and-what-actually-does","show_page_url":"https://stenobird.com/podcast/biohacking-beauty-the-anti-aging-skincare-podcast-1375977","url":"HTTPS://www.younggoose.com","audio_url":"https://episodes.captivate.fm/episode/dcc9ecec-1e42-4961-b9a2-b7f3f6d45c1f.mp3","summary":"Most of what the supplement and skincare industry sells for aging targets one pathway at a time. But your biology does not age that way. It declines across 12 interconnected processes simultaneously, and by the time one of them shows up on your skin, the others have already been running for years. We at Young Goose believe that skin longevity is not a topical problem. It is a whole biology problem, and the ingredients you choose, how they interact, and whether anyone has actually tested them together matters more than any single molecule ever could. In this episode, we are joined for the second time around by Chris Mirabile, founder of NOVOS which is the first biotech company to target all 12 biological causes of aging. Chris collaborates with leading researchers at Harvard and MIT and has built his work around one premise: that real interventions require real testing on real humans, not just promising ingredients. Let's dive in. What's Discussed: (2:14) Why single ingredient marketing is a commercial story, not a scientific one. (9:56) The three hallmarks hitting skin hardest and how they feed each other. (12:02) How UV damage depletes 90% of NAD in the skin from a single exposure event. (22:14) Why stacking molecules requires human testing, not just ingredient research. (33:48) The NOVOS cardiovascular study and results that surprised the researchers. (48:12) Why spending more on your biology does not make your protocol safe. (1:02:18) What omics testing reveals that epigenetics alone cannot tell you. (1:09:45) Where skin longevity is heading in the next five years. Find more from Young Goose: Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com Instagram: @young_goose_skincare…","meta_description":"Most of what the supplement and skincare industry sells for aging targets one pathway at a time. But your biology does not age that way. It declines acros…","key_points":[],"chapters":[],"topics":[],"duration_seconds":3078,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/biohacking-beauty-the-anti-aging-skincare-podcast-1375977/episodes/chris-mirabile-why-one-ingredient-will-never-stop-you-from-aging-and-what-actually-does/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/biohacking-beauty-the-anti-aging-skincare-podcast-1375977/chris-mirabile-why-one-ingredient-will-never-stop-you-from-aging-and-what-actually-does.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}