{"podcast":{"title":"Behind the Genes","slug":"behind-the-genes-3509739","podcast_index_feed_id":3509739,"rss_url":"https://feed.podbean.com/genomicsengland/feed.xml","website_url":"https://genomicsengland.podbean.com","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/10639619/CopyofBehindtheGenestemplates_g5qetz.png","author":"Genomics England","episode_count":100,"summary":"At Genomics England, our vision is a world where everyone benefits from genomic healthcare. From the latest research to the lived experiences of those affected by rare conditions and cancer, Behind the Genes brings you closer to the people behind the science. Each month, we release a deep-dive episode, alongside our Genomics 101 series - short explainers designed to make complex terms in genetics and genomics easier to understand.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/behind-the-genes-3509739"},"episode":{"title":"What if a treatment created for one person could transform care for thousands?","slug":"what-if-a-treatment-created-for-one-person-could-transform-care-for-thousands","published_at":"2026-03-25T08:30:00+00:00","page_url":"https://stenobird.com/podcast/behind-the-genes-3509739/what-if-a-treatment-created-for-one-person-could-transform-care-for-thousands","show_page_url":"https://stenobird.com/podcast/behind-the-genes-3509739","url":"https://genomicsengland.podbean.com/e/what-if-a-treatment-created-for-one-person-could-transform-care-for-thousands/","audio_url":"https://mcdn.podbean.com/mf/web/363jbnb8vmibfg42/Behind_the_Genes_024_What_if_a_treatment_created_for_one_person_could_transform_care_for_thousands.mp3","summary":"In this episode, we explore how individualised medicines are evolving from “n=1” treatments (a treatment effective for a single individual) into approaches that could transform care for many people living with rare conditions. Advances in genomic medicine are making it possible to design highly targeted treatments based on an individual’s genetic information. While these therapies may begin as bespoke solutions for a single patient, they can often be adapted, refined or reused to benefit others with similar conditions. While the research is evolving, the systems needed to deliver these treatments at scale are still catching up. From regulation to access, our guests discuss what needs to change to turn this potential into reality. Our host Sharon Jones, is joined by: Ana Lisa Tavares, Clinical Lead for Rare Disease Research at Genomics England Mel Dixon, Participant Panel member and CEO and Founder of Cure DHDDS If you enjoyed today’s conversation, please like and share wherever you listen to your podcasts. “However rare your condition is, someone has a right to have hope. Everybody should have a hope that we should be able to find a treatment.” You can download the transcript or read it below. Sharon: What if treatments once designed for just one person could now help many others? Thanks to advances in genomic medicine, regulations are changing and research is expanding. This opens up more options for treatments for rare conditions. But what does this mean and how close is real change? I'm Sharon Jones, and this is Behind the Genes. We look at how genomics is changing healthcare, covering everything from cutting-edge research to real-life stories. Individualised medicines are a fast-moving area, but there's still a big gap between scientific progress and what's actuall…","meta_description":"In this episode, we explore how individualised medicines are evolving from “n=1” treatments (a treatment effective for a single individual) into approache…","key_points":[],"chapters":[],"topics":[],"duration_seconds":1629,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/behind-the-genes-3509739/episodes/what-if-a-treatment-created-for-one-person-could-transform-care-for-thousands/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/behind-the-genes-3509739/what-if-a-treatment-created-for-one-person-could-transform-care-for-thousands.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}