{"podcast":{"title":"Behind the Genes","slug":"behind-the-genes-3509739","podcast_index_feed_id":3509739,"rss_url":"https://feed.podbean.com/genomicsengland/feed.xml","website_url":"https://genomicsengland.podbean.com","image_url":"https://pbcdn1.podbean.com/imglogo/image-logo/10639619/CopyofBehindtheGenestemplates_g5qetz.png","author":"Genomics England","episode_count":100,"summary":"At Genomics England, our vision is a world where everyone benefits from genomic healthcare. From the latest research to the lived experiences of those affected by rare conditions and cancer, Behind the Genes brings you closer to the people behind the science. Each month, we release a deep-dive episode, alongside our Genomics 101 series - short explainers designed to make complex terms in genetics and genomics easier to understand.","last_synced_at":null,"page_url":"https://stenobird.com/podcast/behind-the-genes-3509739"},"episode":{"title":"How can genomics help us understand cancer?","slug":"how-can-genomics-help-us-understand-cancer","published_at":"2025-12-17T08:00:00+00:00","page_url":"https://stenobird.com/podcast/behind-the-genes-3509739/how-can-genomics-help-us-understand-cancer","show_page_url":"https://stenobird.com/podcast/behind-the-genes-3509739","url":"https://genomicsengland.podbean.com/e/what-are-inherited-blood-cancers/","audio_url":"https://mcdn.podbean.com/mf/web/yhgrq9y77kyzvjkm/Genomics_101_013_What_is_inherited_blood_cancer.mp3","summary":"In this explainer episode, we’ve asked Dr Katie Snape, principal clinician at Genomics England, cancer geneticist, and specialist in inherited cancer, to explain how genomics can help us understand cancer. You can also find a series of short videos explaining some of the common terms you might encounter about genomics on our YouTube channel. If you’ve got any questions, or have any other topics you’d like us to explain, let us know on podcast@genomicsengland.co.uk. You can download the transcript or read it below. Flo: How can genomics help us understand cancer? I'm Florence Cornish, and today I'm joined with Katie Snape, who is Principal Clinician here at Genomics England, lead Consultant for Cancer Genetics at the Southwest Thames Centre for Genomics, and Chair of UK Cancer Genetics Group. So Katie, it's probably safe to say that everyone listening will have heard the word cancer before. Lots of people may have even been directly affected by it or know someone who has it or who has had it, and I think the term can feel quite scary sometimes and intimidating to understand. So, it might be good if you could explain what we actually mean when we say the word cancer. Katie: Thanks, Florence. So, our bodies are made up of millions of building blocks called cells. Each of these cells contains an instruction manual, and our bodies read this to build a human and keep our bodies working and growing over our lifetimes. So, this human instruction manual is our genetic information, and it's called the human genome. Throughout our lifetime, our cells will continue to divide and grow to make more cells when we need them. And this means that our genetic information has to contain the right instructions, which tell the cells to divide when we need new cells, like making new skin cel…","meta_description":"In this explainer episode, we’ve asked Dr Katie Snape, principal clinician at Genomics England, cancer geneticist, and specialist in inherited cancer, to…","key_points":[],"chapters":[],"topics":[],"duration_seconds":557,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/behind-the-genes-3509739/episodes/how-can-genomics-help-us-understand-cancer/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/behind-the-genes-3509739/how-can-genomics-help-us-understand-cancer.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}