{"podcast":{"title":"Behind the Breakthroughs","slug":"behind-the-breakthroughs-7055075","podcast_index_feed_id":7055075,"rss_url":"https://feeds.acast.com/public/shows/67105af848726944170ab1fe","website_url":"https://shows.acast.com/behind-the-breakthroughs-by-inside-precision-medicine","image_url":"https://assets.pippa.io/shows/67105af848726944170ab1fe/1729176633209-4c042f7e-c9b1-44c7-b2f0-3d36b4c78148.jpeg","author":"Inside Precision Medicine","episode_count":46,"summary":"Join host Jonathan D. Grinstein, PhD, North American Editor for Inside Precision Medicine , as he uncovers the stories behind the pioneers driving the precision medicine revolution. Behind the Breakthroughs features candid interviews with seasoned veterans and rising stars, exploring their origin stories and groundbreaking contributions advancing the frontiers of patient diagnosis, treatment, and care. In every episode, Jonathan goes beyond the science, diving deep into the personal and professional journeys of those striving to make these incredible new therapies more equitable and accessible globally. You'll discover how emerging technologies in molecular diagnostics, next-generation sequencing, genetic medicines (e.g., cell and gene therapies), and AI/ML are transforming treatment and bringing precision medicine closer to the forefront of healthcare. Whether you’re a researcher at a large pharma company or small biotech startup, a clinician at a major health system or community setting, a laboratory technician in the clinic or academia, an investor at a premier or venture capital firm, or just interested in the latest in medicine and healthcare, these interviews will inspire an…","last_synced_at":"2026-07-15T16:19:49.218663+00:00","page_url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075"},"episode":{"title":"Brad Ringeisen: CRISPR for Disease Elimination and Humanitarian Solutions","slug":"brad-ringeisen-crispr-for-disease-elimination-and-humanitarian-solutions","published_at":"2026-02-11T08:01:00+00:00","page_url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075/brad-ringeisen-crispr-for-disease-elimination-and-humanitarian-solutions","show_page_url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075","url":"https://shows.acast.com/behind-the-breakthroughs-by-inside-precision-medicine/episodes/brad-ringeisen-crispr-for-disease-elimination-and-humanitari","audio_url":"https://sphinx.acast.com/p/open/s/67105af848726944170ab1fe/e/698b76520581faffc7699a4e/media.mp3","summary":"CRISPR has crossed a turning point, evolving from an experimental tool into a platform delivering FDA-approved therapies and on-demand patient treatments that correct disease at its source. Brad Ringeisen, a former DARPA office director and leader at the Innovative Genomics Institute (IGI), has been at the center of that transition, helping guide CRISPR from early promise toward scalable clinical impact. Ringeisen discusses in this episode how he is collaborating with CRISPR pioneer and Nobel Prize winner Jennifer Doudna, PhD, at the IGI to address rare, complex, and underserved diseases, going beyond isolated successes. Accessibility, durability, and worldwide benefit, Ringeisen believes, will be the real indicators of CRISPR's success. Produced and hosted by Jonathan D. Grinstein, PhD Audio mixed and mastered by Erick Ziegler Brought to you by Inside Precision Medicine (SAGE Publishing) Hosted on Acast. See acast.com/privacy for more information.","meta_description":"CRISPR has crossed a turning point, evolving from an experimental tool into a platform delivering FDA-approved therapies and on-demand patient treatments…","key_points":[],"chapters":[],"topics":[],"duration_seconds":3459,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/behind-the-breakthroughs-7055075/episodes/brad-ringeisen-crispr-for-disease-elimination-and-humanitarian-solutions/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075/brad-ringeisen-crispr-for-disease-elimination-and-humanitarian-solutions.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}