{"podcast":{"title":"Behind the Breakthroughs","slug":"behind-the-breakthroughs-7055075","podcast_index_feed_id":7055075,"rss_url":"https://feeds.acast.com/public/shows/67105af848726944170ab1fe","website_url":"https://shows.acast.com/behind-the-breakthroughs-by-inside-precision-medicine","image_url":"https://assets.pippa.io/shows/67105af848726944170ab1fe/1729176633209-4c042f7e-c9b1-44c7-b2f0-3d36b4c78148.jpeg","author":"Inside Precision Medicine","episode_count":47,"summary":"Join host Jonathan D. Grinstein, PhD, North American Editor for Inside Precision Medicine , as he uncovers the stories behind the pioneers driving the precision medicine revolution. Behind the Breakthroughs features candid interviews with seasoned veterans and rising stars, exploring their origin stories and groundbreaking contributions advancing the frontiers of patient diagnosis, treatment, and care. In every episode, Jonathan goes beyond the science, diving deep into the personal and professional journeys of those striving to make these incredible new therapies more equitable and accessible globally. You'll discover how emerging technologies in molecular diagnostics, next-generation sequencing, genetic medicines (e.g., cell and gene therapies), and AI/ML are transforming treatment and bringing precision medicine closer to the forefront of healthcare. Whether you’re a researcher at a large pharma company or small biotech startup, a clinician at a major health system or community setting, a laboratory technician in the clinic or academia, an investor at a premier or venture capital firm, or just interested in the latest in medicine and healthcare, these interviews will inspire an…","last_synced_at":"2026-07-29T16:20:06.681896+00:00","page_url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075"},"episode":{"title":"Beaubrun and Acharya: No Antibiotic Without a Diagnostic","slug":"beaubrun-and-acharya-no-antibiotic-without-a-diagnostic","published_at":"2026-07-29T07:00:00+00:00","page_url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075/beaubrun-and-acharya-no-antibiotic-without-a-diagnostic","show_page_url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075","url":"https://shows.acast.com/behind-the-breakthroughs-by-inside-precision-medicine/episodes/beaubrun-and-acharya-the-diagnostic-imperative-for-fighting","audio_url":"https://sphinx.acast.com/p/open/s/67105af848726944170ab1fe/e/6a67a4ff4207b2a601cf89d6/media.mp3","summary":"Antimicrobial resistance (AMR) isn't going to be solved by new antibiotics alone—it also requires identifying resistant infections quickly enough to guide treatment and prevent transmission. In this episode of Behind the Breakthroughs , Anne Beaubrun, PhD, of Cepheid and Amish Acharya, PhD, of the Fleming Initiative, discuss how rapid molecular diagnostics, including the TRACE-CPE study, could bring precision medicine to infectious disease by enabling earlier detection of carbapenemase-producing Enterobacterales (CPE)—dangerous, last-resort antibiotic-resistant bacteria that are spreading rapidly in hospitals. They also explore the scientific, clinical, and policy challenges of making rapid diagnostics a routine part of healthcare worldwide. Produced and hosted by Jonathan D. Grinstein, PhD Audio mixed and mastered by Erick Ziegler Brought to you by Inside Precision Medicine (SAGE Publishing) Hosted on Acast. See acast.com/privacy for more information.","meta_description":"Antimicrobial resistance (AMR) isn't going to be solved by new antibiotics alone—it also requires identifying resistant infections quickly enough to guide…","key_points":[],"chapters":[],"topics":[],"duration_seconds":3505,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/behind-the-breakthroughs-7055075/episodes/beaubrun-and-acharya-no-antibiotic-without-a-diagnostic/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/behind-the-breakthroughs-7055075/beaubrun-and-acharya-no-antibiotic-without-a-diagnostic.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}