{"podcast":{"title":"BackTable Women's Health","slug":"backtable-women-s-health-5805654","podcast_index_feed_id":5805654,"rss_url":"https://feeds.megaphone.fm/BTL9592104236","website_url":"https://www.backtable.com/shows/obgyn","image_url":"https://megaphone.imgix.net/podcasts/1d2e2efa-6055-11ed-bc9a-f7632e26f12c/image/39035e6c83ba78df228200aeac4f81c1.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"BackTable Inc.","episode_count":148,"summary":"The go-to podcast for OBGYNs, gynecologic surgeons, and healthcare professionals focused on women's health. Tune in every week for practical, physician-led conversations on common and complex clinical topics in women's health. Hear how experienced physicians approach real cases, and get practical advice from your peers in your field.","last_synced_at":"2026-07-21T16:18:27.095905+00:00","page_url":"https://stenobird.com/podcast/backtable-women-s-health-5805654"},"episode":{"title":"Ep. 119 Single-Gene NIPT Explained: Clinical Applications & Benefits with Dr. Andrei Rebarber","slug":"ep-119-single-gene-nipt-explained-clinical-applications-benefits-with-dr-andrei-rebarber","published_at":"2026-06-02T07:00:00+00:00","page_url":"https://stenobird.com/podcast/backtable-women-s-health-5805654/ep-119-single-gene-nipt-explained-clinical-applications-benefits-with-dr-andrei-rebarber","show_page_url":"https://stenobird.com/podcast/backtable-women-s-health-5805654","url":"https://traffic.megaphone.fm/BTL1058292618.mp3","audio_url":"https://traffic.megaphone.fm/BTL1058292618.mp3","summary":"How do you decide which noninvasive prenatal testing option is best for your patient, and when should you reach for single-gene NIPT? In this episode of BackTable Women’s Health, host Dr. Nicole Faulkner interviews maternal-fetal medicine specialist Dr. Andrei Rebarber to break down the evolving world of prenatal genetic testing. They discuss the importance of pan-ethnic carrier screening, the clinical scenarios where single-gene NIPT is most useful, and how to navigate counseling and follow-up for a wide range of patients. --- Get the BackTable apphttps://www.backtable.com/app --- This podcast is supported by Naterahttps://www.natera.com/info/fetal-focus --- Timestamps 00:00 - Introduction04:43 - Prenatal Genetic Testing Basics07:10 - Larger Panel Screening Benefits10:49 - Defining Single-Gene NIPT14:51 - Counseling and Invasive Options18:26 - Accuracy Data and No Call Rate22:03 - Patient Acceptance of Test24:18 - When to Test and Screen26:13 - Counseling Carrier Results30:12 - In Utero Treatment 32:36 - Workflow for Generalists35:33 - How to Interpret Literature40:08 - Closing Remarks --- More about this episode Dr. Rebarber shares how witnessing in-utero transfusions for severe Rh disease inspired his career in OBGYN and maternal-fetal medicine, highlighting the importance of treating the fetus as a patient and the rapid growth of fetal therapy. The episode reviews ACOG-guided carrier screening for conditions like cystic fibrosis and hemoglobinopathies, the trend toward larger, pan-ethnic screening panels, and why carrier findings are common but true “double-carrier” couples are relatively rare. Dr. Rebarber also discusses the clinical utility of single-gene NIPT—a cell-free placental DNA test for select recessive conditions—especially when partner testing isn’t pos…","meta_description":"How do you decide which noninvasive prenatal testing option is best for your patient, and when should you reach for single-gene NIPT? In this episode of B…","key_points":[],"chapters":[],"topics":[],"duration_seconds":2553,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/backtable-women-s-health-5805654/episodes/ep-119-single-gene-nipt-explained-clinical-applications-benefits-with-dr-andrei-rebarber/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/backtable-women-s-health-5805654/ep-119-single-gene-nipt-explained-clinical-applications-benefits-with-dr-andrei-rebarber.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}