{"podcast":{"title":"BackTable Women's Health","slug":"backtable-women-s-health-5805654","podcast_index_feed_id":5805654,"rss_url":"https://feeds.megaphone.fm/BTL9592104236","website_url":"https://www.backtable.com/shows/obgyn","image_url":"https://megaphone.imgix.net/podcasts/1d2e2efa-6055-11ed-bc9a-f7632e26f12c/image/39035e6c83ba78df228200aeac4f81c1.png?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress","author":"BackTable Inc.","episode_count":148,"summary":"The go-to podcast for OBGYNs, gynecologic surgeons, and healthcare professionals focused on women's health. Tune in every week for practical, physician-led conversations on common and complex clinical topics in women's health. Hear how experienced physicians approach real cases, and get practical advice from your peers in your field.","last_synced_at":"2026-07-21T16:18:27.095905+00:00","page_url":"https://stenobird.com/podcast/backtable-women-s-health-5805654"},"episode":{"title":"Ep. 109 Hereditary GYN Cancer Syndromes: Practical Screening & Risk-Reduction Guide with Dr. Marcia Ciccone","slug":"ep-109-hereditary-gyn-cancer-syndromes-practical-screening-risk-reduction-guide-with-dr-marcia-ciccone","published_at":"2026-03-24T07:00:00+00:00","page_url":"https://stenobird.com/podcast/backtable-women-s-health-5805654/ep-109-hereditary-gyn-cancer-syndromes-practical-screening-risk-reduction-guide-with-dr-marcia-ciccone","show_page_url":"https://stenobird.com/podcast/backtable-women-s-health-5805654","url":"https://traffic.megaphone.fm/BTL4809054707.mp3","audio_url":"https://traffic.megaphone.fm/BTL4809054707.mp3","summary":"When to test, how to prevent, and what you need to know about hereditary gynecologic cancer syndromes. Two USC gynecologic oncologists, Dr. Mona Guo and Dr. Marcia Ciccone, go in-depth in this BackTable OBGYN x Tumor Board crossover episode. --- Get the BackTable app https://www.backtable.com/app --- Timestamps 00:00 - Introduction01:37 - Why Hereditary Cancer Matters04:51 - Family History Red Flags09:01 - Who Should Order Genetic Testing11:32 - Variants and Counseling Pitfalls13:30 - Access and Remote Testing Options19:27 - BRCA1 Positive Patient Walkthrough24:52 - Risk-Reducing Surgeries29:11 - Prevention and Screening Limits32:38 - Why Ovarian Cancer Is Hard34:04 - Combining Breast and Gyn Surgery35:41 - Preop Ultrasound and CA-12536:27 - BRCA Timing and HRT Nuance42:32 - Nonhormonal Menopause Options47:14 - Lynch Syndrome Screening Basics54:22 - Endometrial Biopsy Debate56:43 - Insurance and Coverage Pitfalls59:00 - Fertility Preservation and REI01:01:41 - Cascade Testing01:02:45 - Conclusion --- More about this episode Dr. Guo and Dr. Ciccone discuss how careful family history can identify patients who may benefit from genetic evaluation and highlight key red flags, including a family history of ovarian cancer, breast cancer at age 50 or younger, and metastatic prostate cancer. They explain the role of genetic counseling, including pre- and post-test discussions and how to approach variants of uncertain significance. They then cover BRCA counseling and risk-reduction strategies, including the timing of risk-reducing bilateral salpingo-oophorectomy, ongoing salpingectomy trials, and considerations for hysterectomy. Additionally, they touch on pathology protocols, breast cancer screening, and the potential protective effect of hormonal contraception. The doctors add…","meta_description":"When to test, how to prevent, and what you need to know about hereditary gynecologic cancer syndromes. Two USC gynecologic oncologists, Dr. Mona Guo and D…","key_points":[],"chapters":[],"topics":[],"duration_seconds":3942,"processing_state":"not_requested","actions":[{"name":"request_transcript","method":"POST","url":"https://stenobird.com/v1/public/podcasts/backtable-women-s-health-5805654/episodes/ep-109-hereditary-gyn-cancer-syndromes-practical-screening-risk-reduction-guide-with-dr-marcia-ciccone/transcription-requests","description":"Idempotently request low-priority transcript generation for this episode."},{"name":"read_markdown","method":"GET","url":"https://stenobird.com/podcast/backtable-women-s-health-5805654/ep-109-hereditary-gyn-cancer-syndromes-practical-screening-risk-reduction-guide-with-dr-marcia-ciccone.md","description":"Read the agent-friendly Markdown representation of this episode resource."}]}}