# 242: The Hormone Dysfunction Epidemic: What GLP-1 Drugs Reveal About Metabolic Health Part 2

Page: https://stenobird.com/podcast/your-longevity-blueprint-292621/242-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-2
Text version: https://stenobird.com/podcast/your-longevity-blueprint-292621/242-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-2.md
Podcast: [Your Longevity Blueprint](https://stenobird.com/podcast/your-longevity-blueprint-292621)
Published: 2026-01-21T08:00:00+00:00
Episode link: https://yourlongevityblueprint.com/the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-2
Audio file: https://traffic.megaphone.fm/HNNOE1816814748.mp3?updated=1768851773
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JSON: https://stenobird.com/v1/public/podcasts/your-longevity-blueprint-292621/episodes/242-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-2
Duration seconds: 2548

## Resource

I’m excited to have Ashley Koff, a registered dietitian with over 25 years of experience in functional and integrative nutrition, with me today for the second part of a two-part series. In Part 1, we explained why your satiety hormones may be underperforming, what that means for aging and longevity, and what you can do today to optimize your metabolic health in a natural way. In Part 2 today, we explore what your best shot for weight loss truly is, why people on GLP-1s lose hair, future options in the pipeline, and the problem with info-obesity. Tips for Optimizing Your Satiety Hormones: Get a structured assessment of your weight, body composition, and bloodwork Ensure your meals are balanced Include a variety of fibers to support your gut bacteria and hormone production Pay attention to your meal timing and frequency Prepare meals that you genuinely enjoy to reinforce your satiety signaling and prevent cravings Bio: Ashley Koff Ashley Koff is a registered dietician and who is the founder of the Better Nutrition Program (BNP), the nutrition course director for UC Irvine’s Susan Samueli Integrative Health Institute’s Integrative and Functional Medicine Fellowship, and a faculty member at the Integrative and Functional Nutrition Academy (IFNA), where she teaches “An Integrative and Functional Nutrition Approach to Obesity and Weight Management.” She is also the author of the upcoming book Your Best Shot (HarperOne, Jan. 6, 2026). A practitioner for more than 25 years, Koff is leading a transformative movement in personalized nutrition, turning “better, not perfect” choices into practical, sustainable strategies that deliver real health outcomes. Through patient stories and personal experience, she shows that optimal health is not just possible — it’s essential to living…

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