# 241: The Hormone Dysfunction Epidemic: What GLP-1 Drugs Reveal About Metabolic Health Part 1 Page: https://stenobird.com/podcast/your-longevity-blueprint-292621/241-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-1 Text version: https://stenobird.com/podcast/your-longevity-blueprint-292621/241-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-1.md Podcast: [Your Longevity Blueprint](https://stenobird.com/podcast/your-longevity-blueprint-292621) Published: 2026-01-14T08:00:00+00:00 Episode link: https://yourlongevityblueprint.com/the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-1 Audio file: https://traffic.megaphone.fm/HNNOE8061311245.mp3?updated=1769006299 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/your-longevity-blueprint-292621/episodes/241-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-1 Duration seconds: 2375 ## Resource What if the explosion of GLP-1 drugs like Ozempic and Wegovy is not a weight loss revolution, but rather a warning sign that something in our metabolic health is fundamentally broken? Today, we take a deep dive into the lesser-known satiety hormones, such as CCK and PYY, exploring how dysfunction in these hormones could be silently accelerating your aging and sabotaging your health span. I’m excited to welcome Ashley Koff, a registered dietitian with more than 25 years of experience in functional and integrative nutrition, for a two-part series. In Part 1 today, we break down why your satiety hormones may be underperforming, how this links to aging and longevity, and simple strategies you can start using today to support metabolic health naturally. How to support your weight-health hormones: Focus on supporting your digestion first, rather than jumping straight into weight loss or metabolic fixes Ensure you’re consuming enough protein and amino acids to support peptide hormone production Reduce gut irritants like alcohol, ultra-processed ingredients, and unnecessary fasting Nourish your body consistently, especially during times of hormonal change, instead of restricting View digestive symptoms as signs of dysfunction instead of problems to push through or ignore Bio: Ashley Koff Ashley Koff is a registered dietician and who is the founder of the Better Nutrition Program (BNP), the nutrition course director for UC Irvine’s Susan Samueli Integrative Health Institute’s Integrative and Functional Medicine Fellowship, and a faculty member at the Integrative and Functional Nutrition Academy (IFNA), where she teaches “An Integrative and Functional Nutrition Approach to Obesity and Weight Management.” She is also the author of the upcoming book Your Best Shot (HarperOne, Jan.… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/your-longevity-blueprint-292621/episodes/241-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-1/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/your-longevity-blueprint-292621/241-the-hormone-dysfunction-epidemic-what-glp-1-drugs-reveal-about-metabolic-health-part-1.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.