# Developing New Therapies Through Partnership, Electricity, and Immunotherapy Page: https://stenobird.com/podcast/touching-base-6714887/developing-new-therapies-through-partnership-electricity-and-immunotherapy Text version: https://stenobird.com/podcast/touching-base-6714887/developing-new-therapies-through-partnership-electricity-and-immunotherapy.md Podcast: [Touching Base](https://stenobird.com/podcast/touching-base-6714887) Published: 2025-09-05T13:50:09+00:00 Episode link: https://shows.acast.com/touching-base/episodes/developing-new-therapies-through-partnership-electricity-and Audio file: https://sphinx.acast.com/p/open/s/65736d39d32e730012c98919/e/68baea94f8dc6bde3858318e/media.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/developing-new-therapies-through-partnership-electricity-and-immunotherapy Duration seconds: 1650 ## Resource Novartis has agreed to license and develop Arrowhead Pharmaceuticals’ preclinical stage small interfering RNA (siRNA) therapy ARO-SNCA, a potential treatment for Parkinson’s disease and other synucleinopathies, plus additional targets. Two stories this week covered very different types of cell reprogramming techniques for therapy development. The first approach may overcome the time delays and safety risks of traditional immunotherapies, especially for patients with aggressive, late-stage disease. Meanwhile, electrical stimulation of macrophages could represent a new therapy to boost the body’s own repair processes in a range of injury and disease situations. Finally, Eli Lilly saw its shares climb 5% this past week after announcing that its history-making oral obesity candidate, orforglipron, aced the Phase III ATTAIN-2 trial. Join GEN editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base : The State of Biotech Summit Registration Novartis Commits Up to $2.2B toward Developing Arrowhead siRNA Therapy Alex Philippidis , GEN Edge, September 2, 2025 Off-the-Shelf Immunotherapy Demonstrates Multipronged Attack Against Cancer GEN, August 29, 2025 Human Macrophages “Reprogrammed” by Electrical Stimulation to Encourage Faster Healing GEN, September 2, 2025 StockWatch: Analysts See $10B+ in Sales for Lilly Oral GLP-1 Alex Philippidis, GEN Edge, September 1, 2025 Touching Base Podcast Hosted by Corinna Singleman, PhD Behind the Breakthroughs Hosted by Jonathan D. Grinstein, PhD Hosted on Acast. See acast.com/privacy for more information. ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/touching-base-6714887/episodes/developing-new-therapies-through-partnership-electricity-and-immunotherapy/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/touching-base-6714887/developing-new-therapies-through-partnership-electricity-and-immunotherapy.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.