# 343: Nucleotides to the Defense

Page: https://stenobird.com/podcast/this-week-in-microbiology-1045713/343-nucleotides-to-the-defense
Text version: https://stenobird.com/podcast/this-week-in-microbiology-1045713/343-nucleotides-to-the-defense.md
Podcast: [This Week in Microbiology](https://stenobird.com/podcast/this-week-in-microbiology-1045713)
Published: 2025-10-25T05:52:09+00:00
Episode link: https://www.microbe.tv/twim/twim-343/
Audio file: https://traffic.libsyn.com/secure/twimshow/TWiM343.mp3?dest-id=53322
Processing state: not_requested
JSON: https://stenobird.com/v1/public/podcasts/this-week-in-microbiology-1045713/episodes/343-nucleotides-to-the-defense
Duration seconds: 2637

## Resource

TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides. Hosts: Michael Schmidt and Mark O. Martin Become a patron of TWiM. Links for this episode: Decoy cyclic nucleotides in phage defense (Nature) CRISPR defense with nucleotides (Nature) A decoy defence molecule to set a trap for viruses (Nature) Cyclic oligonucleotide-based antiphage signaling system immunity (Curr Opin Immunol) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

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## Transcript

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