# On modeling metabolic networks in the brain – with Polina Shichkova  - #35

Page: https://stenobird.com/podcast/theoretical-neuroscience-podcast-6657149/on-modeling-metabolic-networks-in-the-brain-with-polina-shichkova-35
Text version: https://stenobird.com/podcast/theoretical-neuroscience-podcast-6657149/on-modeling-metabolic-networks-in-the-brain-with-polina-shichkova-35.md
Podcast: [Theoretical Neuroscience Podcast](https://stenobird.com/podcast/theoretical-neuroscience-podcast-6657149)
Published: 2025-12-06T06:00:00+00:00
Episode link: https://431c9cd0-a1ff-4f9a-ac41-4fca68240d88.libsyn.com/on-modeling-metabolic-networks-in-the-brain-with-polina-shichkova-35
Audio file: https://traffic.libsyn.com/secure/431c9cd0-a1ff-4f9a-ac41-4fca68240d88/ThN-035-PolinaShichkoval_mixdown.mp3?dest-id=4181327
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Duration seconds: 5498

## Resource

Neurons need particular sodium and potassium concentration gradients across their membranes to function. These gradients are set up by so-called ion pumps which require energy stored in ATP molecules to run. ATP is the common energy currency in the brain and is produced from nutrients delivered by the blood by a complicated set of chemical reactions known as a metabolic network. Today's guest has just published a comprehensive model of such a network and explains how it can shed light on differences between young and brains.

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