# 2420: Poolbeg Pharma - POLB 001 Trial Activated as CRS Prevention Study Moves Into Patients

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Text version: https://stenobird.com/podcast/the-vox-markets-podcast-3914537/2420-poolbeg-pharma-polb-001-trial-activated-as-crs-prevention-study-moves-into-patients.md
Podcast: [The Vox Markets Podcast](https://stenobird.com/podcast/the-vox-markets-podcast-3914537)
Published: 2026-06-12T06:54:27+00:00
Episode link: https://audioboom.com/posts/8915828
Audio file: https://dts.podtrac.com/redirect.mp3/audioboom.com/posts/8915828.mp3?modified=1781247286&sid=5051662&source=rss
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Duration seconds: 231

## Resource

Poolbeg Pharma has announced the activation of the first clinical trial site for its POLB 001 TOPICAL study, marking a key operational milestone for its lead programme. The trial will evaluate POLB 001 as a potential preventative treatment for Cytokine Release Syndrome in relapsed/refractory multiple myeloma patients receiving teclistamab, an approved bispecific antibody. With recruitment now underway and interim data expected in summer 2026, the study could provide an important early readout on POLB 001’s role in improving the safety and accessibility of cancer immunotherapies.

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