# Episode 500: RAS Inhibition in Pancreatic Cancer (yes this is the Uromigos podcast..)

Page: https://stenobird.com/podcast/the-uromigos-1214845/episode-500-ras-inhibition-in-pancreatic-cancer-yes-this-is-the-uromigos-podcast
Text version: https://stenobird.com/podcast/the-uromigos-1214845/episode-500-ras-inhibition-in-pancreatic-cancer-yes-this-is-the-uromigos-podcast.md
Podcast: [The Uromigos](https://stenobird.com/podcast/the-uromigos-1214845)
Published: 2026-05-11T17:46:58+00:00
Episode link: https://podcasters.spotify.com/pod/show/the-uromigos/episodes/Episode-500-RAS-Inhibition-in-Pancreatic-Cancer-yes-this-is-the-Uromigos-podcast-e3j7h0g
Audio file: https://anchor.fm/s/13347ea8/podcast/play/119833040/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-4-11%2F423941717-44100-2-4354664512fed.m4a
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Duration seconds: 2116

## Resource

Filippo Pietrantonio from the National Cancer Institute of Milan joins the podcast to discuss the latest developments in RAS targeting in GI cancers, focusing on the exciting data with daraxonrasib in pancreatic cancer ahead of the ASCO 2026 plenary phase 3 data. We discuss the RAS pathway, prior unsuccessful targeting efforts and nuances on response and resistance.

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## Transcript

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