# Lexi Yoo on Perimenopause, Peptides, and Hormone Strategies That Actually Work

Page: https://stenobird.com/podcast/the-trusted-pharmacist-7273150/lexi-yoo-on-perimenopause-peptides-and-hormone-strategies-that-actually-work
Text version: https://stenobird.com/podcast/the-trusted-pharmacist-7273150/lexi-yoo-on-perimenopause-peptides-and-hormone-strategies-that-actually-work.md
Podcast: [The Trusted Pharmacist](https://stenobird.com/podcast/the-trusted-pharmacist-7273150)
Published: 2026-07-16T07:01:00+00:00
Episode link: https://0ff9d500-e90f-4e0d-b3fb-3684324fb4d0.libsyn.com/lexi-yoo-on-perimenopause-peptides-and-hormone-strategies-that-actually-work
Audio file: https://traffic.libsyn.com/secure/0ff9d500-e90f-4e0d-b3fb-3684324fb4d0/Trusted_Pharmacist_-_Ep_70_-_Dr_Lexi_Yoo_-_A2.mp3?dest-id=4960320
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Duration seconds: 2939

## Resource

Perimenopause, testosterone, estrogen patches, pellets, and peptides are finally getting the attention they should have had years ago. More women are asking better questions. More providers are taking symptoms seriously. And more patients are realizing that brain fog, poor sleep, weight gain, anxiety, joint pain, skin changes, and muscle loss are not things they simply have to tolerate. But this hormone renaissance isn't always a good thing. When every social media post is talking about hormones like they are magic, some very important points and questions get missed. Are we using hormones, peptides, GLP-1s, or regenerative therapies in the right order, for the right patient, with the right testing, the right monitoring, and the right clinical judgment? In this episode, I'm joined by women's health, hormone and peptide expert Lexi Yoo. We talk about what women and practitioners are still getting wrong about hormone therapy, how to think about estrogen delivery when patches are hard to find, and why peptides should sit on top of the foundations rather than replace them. What You'll Discover In This Episode Why women don't have to wait until they are fully menopausal to start talking about hormone therapy The hormone myth Lexi wishes would disappear, especially around testosterone and women's brain health How perimenopause can change cycles, sleep, mood, metabolism, stress tolerance, and body composition Why symptoms matter, but testing still plays a critical role in responsible hormone care Why hormone therapy isn't automatically off-limits for women with a family history of breast cancer Why estrogen patches are becoming harder to find, and what other options may be worth discussing with a knowledgeable provider How pellets can be helpful for some women, and why poor m…

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