# Episode 148: Control of Gene Expression Page: https://stenobird.com/podcast/the-science-of-everything-podcast-533303/episode-148-control-of-gene-expression Text version: https://stenobird.com/podcast/the-science-of-everything-podcast-533303/episode-148-control-of-gene-expression.md Podcast: [The Science of Everything Podcast](https://stenobird.com/podcast/the-science-of-everything-podcast-533303) Published: 2024-09-30T12:34:19+00:00 Episode link: https://www.thescienceofeverything.net/e/episode-148-control-of-gene-expression/ Audio file: https://mcdn.podbean.com/mf/web/5vqrjnkx6a2inhbu/Episode_148_-_Control_of_Gene_Expression6egn6.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/the-science-of-everything-podcast-533303/episodes/episode-148-control-of-gene-expression Duration seconds: 4145 ## Resource An introduction to the processes by which cells control which genes are expressed. We begin with an overview of why genetic regulation is necessary and the key stages where such regulation occurs, including key concepts such as transcription factors and DNA binding domains. We then discuss prokaryotic gene regulation, focusing on the lac operon in E. coli. We then expand the discussion to cover the various mechanisms of eukaryotic gene regulation, including chromatic remodelling, transcriptional regulation, post-transcriptional regulation, RNA editing, and micro RNAs. Recommended pre-listening is Episodes 34-35: DNA Structure and Function, and Episode 118: Cell Signalling. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-science-of-everything-podcast-533303/episodes/episode-148-control-of-gene-expression/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/the-science-of-everything-podcast-533303/episode-148-control-of-gene-expression.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.