# Dr. Mimi Shirasu-Hiza: Can Meal Timing Slow Aging?

Page: https://stenobird.com/podcast/the-reprogram-7585130/dr-mimi-shirasu-hiza-can-meal-timing-slow-aging
Text version: https://stenobird.com/podcast/the-reprogram-7585130/dr-mimi-shirasu-hiza-can-meal-timing-slow-aging.md
Podcast: [The ReProgram](https://stenobird.com/podcast/the-reprogram-7585130)
Published: 2026-07-06T16:00:00+00:00
Episode link: https://podcasters.spotify.com/pod/show/thereprogrampodcast/episodes/Dr--Mimi-Shirasu-Hiza-Can-Meal-Timing-Slow-Aging-e3lmnui
Audio file: https://anchor.fm/s/10b3944a8/podcast/play/122428818/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-6-5%2F427412078-44100-2-60332e5885f42.mp3
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JSON: https://stenobird.com/v1/public/podcasts/the-reprogram-7585130/episodes/dr-mimi-shirasu-hiza-can-meal-timing-slow-aging
Duration seconds: 802

## Resource

🧠 Episode Overview What if aging is shaped not only by what you eat, how much you exercise, or which genes you inherit — but also by when your body does things each day?In this episode of The ReProgram, Dr. George Murphy sits down with Dr. Mimi Shirasu-Hiza at the Gordon Research Conference Systems Aging Meeting in Maine.Dr. Shirasu-Hiza is a Professor of Genetics and Development at Columbia University and an international expert in circadian gene regulation, aging, and health.This conversation explores circadian rhythms as daily, approximately 24-hour oscillations in gene expression, tissue function, and behavior — and why disruption of those rhythms through shift work, jet lag, irregular sleep, or mistimed eating may affect metabolism, cardiovascular risk, obesity, cancer risk, and aging biology.A major focus is time-restricted eating: not simply eating less, but aligning eating and fasting with the body’s active and resting phases. Dr. Shirasu-Hiza discusses work in fruit flies showing that time-restricted eating can extend lifespan and preserve youthful oscillations in genes involved in metabolism, protein translation, immune defense, stress response, and other core biological programs. 🔑 Keywords Circadian rhythms, circadian clock, biological rhythms, time-restricted eating, intermittent fasting, caloric restriction, meal timing, fasting window, overnight fasting, metabolism, cardiovascular disease, obesity, cancer risk, aging biology, longevity science, geroscience, exercise, healthspan, resilience, ReProgram Podcast, Dr. George Murphy 🧠 Takeaways • Circadian rhythms are daily, approximately 24-hour oscillations in gene expression, tissue function, and behavior. • The circadian clock is not just about sleep; it helps coordinate transcription, metabolism, feeding,…

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