# 387: Challenges for a crucial sickle cell treatment and the latest outlook for GLP-1s

Page: https://stenobird.com/podcast/the-readout-loud-1134305/387-challenges-for-a-crucial-sickle-cell-treatment-and-the-latest-outlook-for-glp-1s
Text version: https://stenobird.com/podcast/the-readout-loud-1134305/387-challenges-for-a-crucial-sickle-cell-treatment-and-the-latest-outlook-for-glp-1s.md
Podcast: [The Readout Loud](https://stenobird.com/podcast/the-readout-loud-1134305)
Published: 2026-02-05T20:49:00+00:00
Episode link: https://traffic.megaphone.fm/TTSAA7740815504.mp3?updated=1770325297
Audio file: https://traffic.megaphone.fm/TTSAA7740815504.mp3?updated=1770325297
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JSON: https://stenobird.com/v1/public/podcasts/the-readout-loud-1134305/episodes/387-challenges-for-a-crucial-sickle-cell-treatment-and-the-latest-outlook-for-glp-1s
Duration seconds: 1684

## Resource

On this week’s episode of The Readout LOUD: two starkly different financial outlooks from Novo Nordisk and Eli Lilly, a psychedelics drug from Compass Pathways encountered a roadblock with the Trump White House, and a closer look at why manufacturing problems have slowed the rollout of a crucial sickle cell treatment. It’s our pre-Super Bowl show, which triggered some co-host squabbling. Adam Feuerstein is all Patriots, Elaine Chen is Team Seahawks, while Allison DeAngelis, raised in Seattle but now a Boston denizen, struggles with dual loyalties. Our special guest this week is STAT reporter Jason Mast. And if you get a chance, wish Adam a happy birthday.

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## Transcript

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