# 53 – Too LITTLE or Too MUCH: Addison’s vs. Cushing’s Disease in Dogs Page: https://stenobird.com/podcast/the-marty-laura-show-7153313/53-too-little-or-too-much-addison-s-vs-cushing-s-disease-in-dogs Text version: https://stenobird.com/podcast/the-marty-laura-show-7153313/53-too-little-or-too-much-addison-s-vs-cushing-s-disease-in-dogs.md Podcast: [The Marty & Laura Show](https://stenobird.com/podcast/the-marty-laura-show-7153313) Published: 2025-12-17T16:00:00+00:00 Episode link: https://martyandlaurashow.com//53-too-little-or-too-much-addisons-vs-cushings-disease-in-dogs Audio file: https://episodes.captivate.fm/episode/8b83208f-d0fd-4f3a-a3b3-a60d6b6a9a64.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/the-marty-laura-show-7153313/episodes/53-too-little-or-too-much-addison-s-vs-cushing-s-disease-in-dogs Duration seconds: 1688 ## Resource Too LITTLE or Too MUCH: Addison’s vs. Cushing’s Disease in Dogs In this episode, Marty and Laura dive into two often-confused but fundamentally opposite adrenal diseases in dogs: Addison’s disease (hypoadrenocorticism) and Cushing’s disease (hyperadrenocorticism) . While both involve the adrenal glands, one is caused by too little hormone production and the other by too much . Marty explains the anatomy and function of the adrenal glands, how these diseases present very differently in real life, and why they can be so challenging to diagnose and manage. The conversation also addresses common misconceptions around genetics and breeding, emphasizing that even dogs from excellent breeding programs can develop these conditions. With real-world examples, including Laura’s own dogs, the episode highlights symptoms to watch for, diagnostic challenges, treatment options, long-term prognosis, and why careful veterinary monitoring is essential. The discussion expands into related conditions like diabetes and kidney disease, underscoring an important message: similar symptoms can point to very different underlying problems, and accurate diagnosis matters. 5 Key Takeaways 1. Addison’s and Cushing’s Are Opposites — But Equally Serious Addison’s disease occurs when the adrenal glands don’t produce enough hormones, often causing sudden, severe illness. Cushing’s disease is caused by excess cortisol and develops slowly over months or even years. Despite affecting the same body system, they look and behave very differently. 2. You Can’t Always “Breed Away” From These Diseases While some breeds (like Poodles and Nova Scotia Duck Tolling Retrievers) show higher incidence, there is no universal genetic test for Addison’s or Cushing’s. Even carefully bred dogs from responsible programs can… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-marty-laura-show-7153313/episodes/53-too-little-or-too-much-addison-s-vs-cushing-s-disease-in-dogs/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/the-marty-laura-show-7153313/53-too-little-or-too-much-addison-s-vs-cushing-s-disease-in-dogs.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.