# Is it Anxiety or Lyme? PANS/PANDAS, Neuroinflammation, and Pediatric Chronic Illness with Dr. Somer DelSignore Page: https://stenobird.com/podcast/the-lyme-podcast-7049299/is-it-anxiety-or-lyme-pans-pandas-neuroinflammation-and-pediatric-chronic-illness-with-dr-somer-delsignore Text version: https://stenobird.com/podcast/the-lyme-podcast-7049299/is-it-anxiety-or-lyme-pans-pandas-neuroinflammation-and-pediatric-chronic-illness-with-dr-somer-delsignore.md Podcast: [The Lyme+ Podcast](https://stenobird.com/podcast/the-lyme-podcast-7049299) Published: 2026-05-21T19:01:08+00:00 Episode link: https://podcasters.spotify.com/pod/show/lymeplus/episodes/Is-it-Anxiety-or-Lyme--PANSPANDAS--Neuroinflammation--and-Pediatric-Chronic-Illness-with-Dr--Somer-DelSignore-e3jna05 Audio file: https://anchor.fm/s/fb769cc8/podcast/play/120350149/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-4-21%2F424635971-44100-2-bdd8235eb8d13.m4a Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/the-lyme-podcast-7049299/episodes/is-it-anxiety-or-lyme-pans-pandas-neuroinflammation-and-pediatric-chronic-illness-with-dr-somer-delsignore Duration seconds: 2828 ## Resource What happens when a vibrant, energetic child suddenly faces severe anxiety, mood changes, OCD, or physical tics? Today on Lyme+ , Kenzie Vath and Dan Wagner sit down with integrative pediatrician Dr. Somer DelSignore to pull back the rug on a hidden epidemic: pediatric neuroinflammation. When a child's personality flips overnight, mainstream medicine frequently rushes to a purely psychiatric label. But as Dr. Sommer explains, the nervous system does not exist in a vacuum. In this episode, we dive into the clinical reality of PANS and PANDAS , why commercial laboratory blood tests miss up to 50% of active tick-borne pathogens, and how stealth infections like Borrelia , Bartonella , and Babesia can cross a child's vulnerable blood-brain barrier to trigger an autoimmune attack on the brain. We also break down the hard data surrounding congenital Lyme and map out a comprehensive, root-cause protocol to restore a child's health from the cell up. The views expressed by guests are based on their personal clinical experiences and research. This podcast is for educational and storytelling purposes only and does not constitute medical advice. Global Lyme Alliance does not endorse specific alternative treatments, private laboratory facilities, or commercial health products. Always consult with a qualified, literate healthcare professional for pediatric diagnosis and treatment. Connect with Global Lyme Alliance Dr. Somer Delsignore: Hudson Integrative Health Instagram: @ drsomerdelsignore Connect with Global Lyme Alliance (GLA): Website: GLA.org Instagram: @GlobalLymeAlliance ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-lyme-podcast-7049299/episodes/is-it-anxiety-or-lyme-pans-pandas-neuroinflammation-and-pediatric-chronic-illness-with-dr-somer-delsignore/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/the-lyme-podcast-7049299/is-it-anxiety-or-lyme-pans-pandas-neuroinflammation-and-pediatric-chronic-illness-with-dr-somer-delsignore.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.