# Discussing RA: UPA outcomes and the impact of GCs on targeted therapies in RA Page: https://stenobird.com/podcast/the-imid-forum-981476/discussing-ra-upa-outcomes-and-the-impact-of-gcs-on-targeted-therapies-in-ra Text version: https://stenobird.com/podcast/the-imid-forum-981476/discussing-ra-upa-outcomes-and-the-impact-of-gcs-on-targeted-therapies-in-ra.md Podcast: [The IMID Forum](https://stenobird.com/podcast/the-imid-forum-981476) Published: 2025-12-18T14:52:48+00:00 Episode link: https://soundcloud.com/imidforum/discussing-ra-upa-outcomes-and-the-impact-of-gcs-on-targeted-therapies-in-ra Audio file: https://feeds.soundcloud.com/stream/2231964713-imidforum-discussing-ra-upa-outcomes-and-the-impact-of-gcs-on-targeted-therapies-in-ra.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/the-imid-forum-981476/episodes/discussing-ra-upa-outcomes-and-the-impact-of-gcs-on-targeted-therapies-in-ra Duration seconds: 1350 ## Resource Join Professor Iain McInnes for the latest episode of Discussing RA on The Immune-Mediated Inflammatory Disease Forum. In this episode, he and Doctor Reike Alten will be reviewing two papers. The first paper by Kameda et al. assessed long-term safety and efficacy of UPA over 5 years in Japanese patients with moderate-to- severe active RA and an inadequate response to stable doses of csDMARDs-IR. The second paper by Salvato et al. assessed the impact of chronic oral low-dose GCs on the efficacy and retention rates of JAK inhibitors compared to other mechanisms of action therapies in a cohort of RA patients with inadequate response to TNFi. ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-imid-forum-981476/episodes/discussing-ra-upa-outcomes-and-the-impact-of-gcs-on-targeted-therapies-in-ra/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/the-imid-forum-981476/discussing-ra-upa-outcomes-and-the-impact-of-gcs-on-targeted-therapies-in-ra.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.