# BONUS: The Anti-Aging Molecule Backed by Nobel Prize Research : 1492 Page: https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/bonus-the-anti-aging-molecule-backed-by-nobel-prize-research-1492 Text version: https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/bonus-the-anti-aging-molecule-backed-by-nobel-prize-research-1492.md Podcast: [The Human Upgrade: Biohacking for Longevity & Performance](https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629) Published: 2026-06-28T08:30:00+00:00 Episode link: https://dts.podtrac.com/redirect.mp3/mgln.ai/e/p394/rss.art19.com/episodes/084de429-e5b3-48e1-84de-d2c97281e07d.mp3?rss_browser=BAhJIg90cmFuc2NyaWJyBjoGRVQ%3D--952c5701c84ad333c69d5faa668f8177091704f0 Audio file: https://dts.podtrac.com/redirect.mp3/mgln.ai/e/p394/rss.art19.com/episodes/084de429-e5b3-48e1-84de-d2c97281e07d.mp3?rss_browser=BAhJIg90cmFuc2NyaWJyBjoGRVQ%3D--952c5701c84ad333c69d5faa668f8177091704f0 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/the-human-upgrade-biohacking-for-longevity-performance-1031629/episodes/bonus-the-anti-aging-molecule-backed-by-nobel-prize-research-1492 Duration seconds: 745 ## Resource You already know something has changed - the energy crashes, the slow recovery, the brain fog that wasn't there ten years ago. Most people assume that's just aging. But it’s NOT. Nobel Prize-winning research has identified a single molecule that controls how fast your body breaks down, and more importantly, exactly why yours is being destroyed faster than it's being rebuilt. The fix isn't complicated, but the order you do it in matters. In this video, Dave breaks down what this molecule is, why your body is actively working against it, and the exact protocol (diet, fasting, exercise, and supplementation) to restore it before the gap gets any wider. Thank you to our sponsors! Gatlan | Book your free consultation at  www.gatlan.com/DAVE Viome | Check it out at  viome.com  and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body. iRestore | Reverse hair loss at  www.irestore.com/DAVE  and get exclusive savings on the iRestore Elite, use code DAVE Timestamps: 0:00 – The Longevity Switch 0:47 – Why Mitochondria Matter 2:28 – What Mitophagy Is 2:46 – How Mitophagy Works 4:18 – What Shuts It Off 8:54 – The Damage Compounds 9:22 – How to Turn It Back On 10:31 – Signal 1: Fasting 11:48 – Signal 2: Exercise (REHIT) 12:30 – Signal 3: Cold Exposure 13:22 – Signal 4: NAD+ 14:29 – Signal 5: Urolithin A and Spermidine Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Danger Cof… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-human-upgrade-biohacking-for-longevity-performance-1031629/episodes/bonus-the-anti-aging-molecule-backed-by-nobel-prize-research-1492/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/bonus-the-anti-aging-molecule-backed-by-nobel-prize-research-1492.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.