# BDNF Superpowers Through MDMA and Ketamine | Dr. Dave Rabin : 1486 Page: https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/bdnf-superpowers-through-mdma-and-ketamine-dr-dave-rabin-1486 Text version: https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/bdnf-superpowers-through-mdma-and-ketamine-dr-dave-rabin-1486.md Podcast: [The Human Upgrade: Biohacking for Longevity & Performance](https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629) Published: 2026-06-18T08:30:00+00:00 Episode link: https://daveasprey.com/1413-dave-rabin/ Audio file: https://dts.podtrac.com/redirect.mp3/mgln.ai/e/p394/rss.art19.com/episodes/452bb77c-7dd0-4ad6-8390-23351d4e04d0.mp3?rss_browser=BAhJIg90cmFuc2NyaWJyBjoGRVQ%3D--952c5701c84ad333c69d5faa668f8177091704f0 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/the-human-upgrade-biohacking-for-longevity-performance-1031629/episodes/bdnf-superpowers-through-mdma-and-ketamine-dr-dave-rabin-1486 Duration seconds: 3662 ## Resource Ketamine Therapy, MDMA, Psilocybin, and the Science of Psychedelic Assisted Healing  Most people struggling with depression, anxiety, and trauma have never felt safe in their nervous system, and the treatments they have been prescribed are making that worse. This episode breaks down the neuroscience of psychedelic therapy, why ketamine is the safest and most accessible starting point, how MDMA triggers a BDNF dependent pathway that repairs trauma all the way down to the epigenetic code, and why your antidepressant may be blocking the very brain states required for real healing.  -Watch this episode on YouTube for the full video experience:  https://www.youtube.com/@DaveAspreyBPR   -Order Dr. Rabin’s Book ‘ A Simple Guide to Being Alive’:  https://apolloneuro.com/pages/a-simple-guide-to-being-alive   Host Dave Asprey sits down with Dr. Dave Rabin, MD, PhD, a senior research scientist at the Florida Institute for Human and Machine Cognition, Executive Director of The Board of Medicine, and co-founder and Chief Medical Officer of Apollo Neuroscience. Dr. Rabin received his MD and PhD in neuroscience from Albany Medical College and specialized in psychiatry at the University of Pittsburgh Medical Center. He has spent 20 years studying chronic stress and non-invasive therapies for treatment-resistant illness, and his primary research on MDMA assisted therapy for severe PTSD has demonstrated that trauma can be reversed at the epigenetic level, offering a genuine path to a cure. His upcoming book A Simple Guide to Being Alive publishes June 1, 2026 and is a science-backed manual for anyone who has ever felt overwhelmed by the modern world.    Dave and Dr. Rabin break down why nearly 50% of people… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-human-upgrade-biohacking-for-longevity-performance-1031629/episodes/bdnf-superpowers-through-mdma-and-ketamine-dr-dave-rabin-1486/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/the-human-upgrade-biohacking-for-longevity-performance-1031629/bdnf-superpowers-through-mdma-and-ketamine-dr-dave-rabin-1486.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.