# How Chronic Stress Drives Autoimmune Disease (The Science Most Doctors Miss)

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Text version: https://stenobird.com/podcast/the-goode-health-functional-medicine-longevity-autoimmune-6433631/how-chronic-stress-drives-autoimmune-disease-the-science-most-doctors-miss.md
Podcast: [The Goode Health: Functional Medicine, Longevity & Autoimmune](https://stenobird.com/podcast/the-goode-health-functional-medicine-longevity-autoimmune-6433631)
Published: 2026-03-16T07:30:00+00:00
Episode link: https://www.nicolegoodehealth.com
Audio file: https://episodes.captivate.fm/episode/2bb03cbd-8c0c-44ed-8f48-e17f8006f7ab.mp3
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Duration seconds: 1833

## Resource

You’ve probably been told at some point to “manage your stress.” But what does that actually mean, and why does chronic stress have such a powerful effect on the immune system? In this episode of The Goode Health Podcast, we break down the science behind the connection between stress and autoimmune disease , and why it’s one of the most overlooked drivers of immune dysfunction in modern medicine. 00:00 — Stress Is Present in Nearly Every Autoimmune Case 02:12 — Psychoneuroimmunology Explained: How Stress Affects the Immune System 07:07 — The 3 Biological Mechanisms Linking Chronic Stress And Autoimmune Disease 14:00 — Real Clinical Stories: How Stress Triggers Autoimmune Flares 22:10 — Why “You need to manage your stress” Isn’t Enough 26:10 — Practical Strategies To Support the Stress–Immune System Connection You’ll also hear real clinical cases showing how addressing stress physiology, adrenal function, gut health, and inflammation can improve symptom patterns and reduce autoimmune flares. If you’ve ever noticed your symptoms worsen during stressful periods or felt like your treatment plan is missing something important, this episode will help you understand what’s happening inside your body, and why addressing chronic stress is a critical part of autoimmune care. RESOURCES: Grab all the links and resources mentioned in this episode at https://www.nicolegoodehealth.com/the-goode-health-podcast/episode-117 DISCLAIMER: The content in this podcast and related website is not intended to be a substitute for medical advice. It is not intended to be used to diagnose or treat, instead it is designed to help educate and inspire. Always seek the advice of a professional medical practitioner or qualified health practitioner. Never ignore or disregard advice given to you based on…

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