# Episode 145: Myeloma Series, Pt. 6 - First line treatment of Multiple Myeloma (2026)

Page: https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989/episode-145-myeloma-series-pt-6-first-line-treatment-of-multiple-myeloma-2026
Text version: https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989/episode-145-myeloma-series-pt-6-first-line-treatment-of-multiple-myeloma-2026.md
Podcast: [The Fellow on Call: The Heme/Onc Podcast](https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989)
Published: 2026-01-21T09:00:00+00:00
Episode link: https://www.thefellowoncall.com/tfocpodcast/myelomafirstlinetreatment
Audio file: https://static1.squarespace.com/static/61b273ac9be6aa2250498c9e/t/696d6cd9f42ec4369ddfeb81/1771881248828/TFOC_Myeloma+Front+Line+Treatment_mix.mp3
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## Resource

This week, we begin our discussion about treatment of multiple myeloma, focusing on the first-line setting. Once again, a lot has changed in this space over the last few years, most notably the standards of care (now quadruplet regimens instead of triplet regimens!). We break down the data and how to help you practically approach your treatment planning for your patient with newly diagnosed multiple myeloma. Content: - What are the phases of treatment for multiple myeloma - What are our current treatment standards of care? - How do we select the agents to include in our first-line regimens? - How do we stratify patients into quadruplet vs. triplet eligible? What about transplant eligible vs. ineligible? ** This episode is sponsored by Primum! To learn more, sign up for your free account, and to ask questions to Primum experts, visit primum.co/fellows ** Want to review the show notes for this episode and others? Check out our website. Love what you hear? Tell a friend and leave a review on our podcast streaming platforms! Twitter: @TheFellowOnCall Instagram: @TheFellowOnCall Listen in on: Apple Podcast, Spotify, and Youtube

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## Transcript

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