# Episode 141: Myeloma Series, Pt.2 - Intro to MGUS and Smoldering Myeloma (2025)

Page: https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989/episode-141-myeloma-series-pt-2-intro-to-mgus-and-smoldering-myeloma-2025
Text version: https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989/episode-141-myeloma-series-pt-2-intro-to-mgus-and-smoldering-myeloma-2025.md
Podcast: [The Fellow on Call: The Heme/Onc Podcast](https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989)
Published: 2025-12-10T09:00:00+00:00
Episode link: https://www.thefellowoncall.com/tfocpodcast/mgusssmintro2025
Audio file: https://static1.squarespace.com/static/61b273ac9be6aa2250498c9e/t/6929c23250eff25e13f18f01/1765735644131/MGUS+and+SMM+2025+Updates_Final.mp3
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## Resource

In today’s episode, we continue our myeloma series, this time we’ll delve deeper into the spectrum of plasma cell dyscrasias, including defining MGUS, discussing surveillance of MGUS, defining smoldering myeloma (SM). We are slowly inching our discussion towards the diagnosis of Multiple myeloma (MM)! Content: - Defining MGUS - Discussing risk of progression of MGUS to MM - How to interpret free light chains in renal failure - How do we monitor MGUS patients? - When do we do additional testing in MGUS? - What is smoldering myeloma? - What are myeloma defining events? - How do we risk stratify SM patients? - How do we monitor SM patients? Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodes This episode has been sponsored by Primum. To sign up for a free account, check out: tfoc.primum.co ** Want to review the show notes for this episode and others? Check out our website: Love what you hear? Tell a friend and leave a review on our podcast streaming platforms! Twitter: @TheFellowOnCall Instagram: @TheFellowOnCall Listen in on: Apple Podcast, Spotify, and Youtube

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