# Episode 140: Myeloma Series, Pt.1 - Intro to Testing and MGUS (2025)

Page: https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989/episode-140-myeloma-series-pt-1-intro-to-testing-and-mgus-2025
Text version: https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989/episode-140-myeloma-series-pt-1-intro-to-testing-and-mgus-2025.md
Podcast: [The Fellow on Call: The Heme/Onc Podcast](https://stenobird.com/podcast/the-fellow-on-call-the-heme-onc-podcast-4669989)
Published: 2025-12-03T09:00:00+00:00
Episode link: https://www.thefellowoncall.com/tfocpodcast/mmintroandmgus2025
Audio file: https://static1.squarespace.com/static/61b273ac9be6aa2250498c9e/t/6929adac042aad5e42b4fac8/1764339156376/Intro+to+Myeloma+2025+Updates_Final.mp3
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## Resource

It’s been 3 years since our last myeloma series updates and the reality is, a lot has changed! Instead of releasing an updates episode, we are redoing our prior myeloma series to make sure that you, our listeners, can follow along the way you always have. In the first episode in our highly-anticipated multiple myeloma series, we begin our discussion about introduction to testing/workup for plasma cell dyscrasias and having our initial discussion about monoclonal gammopathy of undetermined significance (MGUS). Contents: - What is a plasma cell ? - What is a plasma cell dyscrasia? - What is an "SPEP"? -What is "immunofixation"? -What are "serum free light chains"? -Checking UPEP -Does everyone need a bone marrow biopsy and/or additional workup? -What is MGUS? ** Want to review the show notes for this episode and others? Check out our website: Love what you hear? Tell a friend and leave a review on our podcast streaming platforms! Twitter: @TheFellowOnCall Instagram: @TheFellowOnCall Listen in on: Apple Podcast, Spotify, and Youtube

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## Transcript

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