# Seasonal Allergies, Histamine, and the OTC Drug Combo That Backfires | With Steve

Page: https://stenobird.com/podcast/the-evolving-wellness-podcast-with-sarah-kleiner-wellness-2136142/seasonal-allergies-histamine-and-the-otc-drug-combo-that-backfires-with-steve
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Podcast: [The Evolving Wellness Podcast with Sarah Kleiner Wellness](https://stenobird.com/podcast/the-evolving-wellness-podcast-with-sarah-kleiner-wellness-2136142)
Published: 2026-05-27T11:00:00+00:00
Episode link: https://podcasters.spotify.com/pod/show/sarahkleinerwellness/episodes/Seasonal-Allergies--Histamine--and-the-OTC-Drug-Combo-That-Backfires--With-Steve-e3js556
Audio file: https://anchor.fm/s/48b7c51c/podcast/play/120509030/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-4-25%2F424846001-44100-2-e9c0536ed5809.mp3
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Duration seconds: 3656

## Resource

On the Evolving Wellness podcast, host Sarah Kleiner interviews returning guest Steve about seasonal allergies, histamine intolerance, and MCAS, emphasizing that the root problem is often loss of immune tolerance driven by gut dysbiosis, leaky gut, and Th1/Th2 imbalance from factors like antibiotics, PPIs, stress, mold, and environmental changes. They contrast symptom tools—antihistamines that block histamine receptors and herbs like quercetin/ginger that stabilize mast cells—with approaches aimed at lowering IgE formation and retraining gut–immune “crosstalk.” Steve describes postbiotics and beta-glucans as “tolerization rehab,” highlighting his product HoloImmune (heat-killed strains) and butyrate (TriButyrin-X) for gut lining and mast cell support, plus DAO enzymes for dietary histamine. They discuss safety, dosing, avoiding live probiotics during flares, and examples including motion sickness, bug-bite welts, and a child’s post-viral hives. — GUT HEALTH: Healthy Gut Supplements- discount automatically applied: Holoimmune: https://healthygut.com/holoimmune-now/?rstr=811&coupon_code=Sarah15 Holozyme Link: https://healthygut.com/holozyme-now/?rstr=811&coupon_code=Sarah15 HCL Guard Link: https://healthygut.com/hcl-guard-now/?rstr=811&coupon_code=Sarah15 Tributyrin X: https://healthygut.com/tributyrin-x-now/?rstr=811&coupon_code=Sarah15 Magnesium: https://healthygut.com/magnesiumhp-now/?rstr=811&coupon_code=Sarah15 _________ Sponsored By: → VivaRays | This episode is sponsored by VivaRays - VivaRays Blue - code YOGI https://vivarays.com/ → Bon Charge | Go to https://boncharge.com/products/demi-red-light-device?rfsn=8108115.26608d & use code SARAHKLEINER for 15% off storewide. _________ Timestamp: 00:00 Coming Up 01:02 Podcast Intro Disclaimer 02:…

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