# The Broccoli Molecule That Steers Estrogen Down the Right Pathway | Mara Labs Page: https://stenobird.com/podcast/the-dr-tyna-show-4119597/the-broccoli-molecule-that-steers-estrogen-down-the-right-pathway-mara-labs Text version: https://stenobird.com/podcast/the-dr-tyna-show-4119597/the-broccoli-molecule-that-steers-estrogen-down-the-right-pathway-mara-labs.md Podcast: [The Dr. Tyna Show](https://stenobird.com/podcast/the-dr-tyna-show-4119597) Published: 2026-04-30T06:00:00+00:00 Episode link: https://mgln.ai/e/1458/pscrb.fm/rss/p/tracking.swap.fm/track/hQzRUk5FlBqiODHZblrZ/mgln.ai/e/p500242/traffic.megaphone.fm/SSM1534721143.mp3?updated=1777585468 Audio file: https://mgln.ai/e/1458/pscrb.fm/rss/p/tracking.swap.fm/track/hQzRUk5FlBqiODHZblrZ/mgln.ai/e/p500242/traffic.megaphone.fm/SSM1534721143.mp3?updated=1777585468 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/the-dr-tyna-show-4119597/episodes/the-broccoli-molecule-that-steers-estrogen-down-the-right-pathway-mara-labs Duration seconds: 5087 ## Resource EP. 259: Join my NEW community for Gen X women: ⁠https://www.skool.com/drtyna/about⁠ What if one compound from broccoli could influence detox pathways, estrogen metabolism, gut integrity, and even how your body handles modern environmental toxins like microplastics? In this episode, I sit down with David Roberts and Dr. John Gilday from Mara Labs to break down sulforaphane and why it plays such a unique role in metabolic and hormonal health. We talk about estrogen metabolism, NRF2 activation, inflammation signaling, gut barrier function, and emerging research around microplastics and cellular detox systems.→ For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off. Topics Discussed: → How does sulforaphane affect detox pathways → What does NRF2 do in the body → Can supplements help estrogen metabolism → How do microplastics affect hormones → What improves gut barrier function Sponsored By: → Mara Labs | For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off. On This Episode We Cover:  → 00:00:00 - Introduction  → 00:03:32 - Estrogen + Metabolism   → 00:06:54 - AMPK + SIRT 1   → 00:12:42 - Supplement Comparisons  → 00:17:47 - Cooked vs Raw Broccoli  → 00:23:33 - Detox Phases  → 00:27:13 - Microdosing GLP1  → 00:29:11 - Leaky Gut + Glyphosate  → 00:31:51 - Sauna + Red Light  → 00:34:21 - Alcohol + Hangovers  → 00:35:18 - Exercise Performance + Recovery → 00:39… ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/the-dr-tyna-show-4119597/episodes/the-broccoli-molecule-that-steers-estrogen-down-the-right-pathway-mara-labs/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/the-dr-tyna-show-4119597/the-broccoli-molecule-that-steers-estrogen-down-the-right-pathway-mara-labs.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.