# Zoledronate (Reclast) for 10 Years: Fracture Prevention at What Cost to Bone Turnover?

Page: https://stenobird.com/podcast/the-dr-doug-show-6678750/zoledronate-reclast-for-10-years-fracture-prevention-at-what-cost-to-bone-turnover
Text version: https://stenobird.com/podcast/the-dr-doug-show-6678750/zoledronate-reclast-for-10-years-fracture-prevention-at-what-cost-to-bone-turnover.md
Podcast: [The Dr. Doug Show](https://stenobird.com/podcast/the-dr-doug-show-6678750)
Published: 2026-02-09T16:00:01+00:00
Episode link: https://podcasters.spotify.com/pod/show/douglas-lucas0/episodes/Zoledronate-Reclast-for-10-Years-Fracture-Prevention-at-What-Cost-to-Bone-Turnover-e3erm7c
Audio file: https://anchor.fm/s/df8b04cc/podcast/play/115250860/https%3A%2F%2Fd3ctxlq1ktw2nl.cloudfront.net%2Fstaging%2F2026-1-9%2F417762401-44100-2-f0256ea37e193.mp3
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JSON: https://stenobird.com/v1/public/podcasts/the-dr-doug-show-6678750/episodes/zoledronate-reclast-for-10-years-fracture-prevention-at-what-cost-to-bone-turnover
Duration seconds: 838

## Resource

In this video, Dr. Doug Lucas breaks down a recent New England Journal of Medicine study examining long-term use of the bisphosphonate zoledronate (Reclast) for fracture prevention. He explains how infrequent dosing over 10 years reduced vertebral fractures, but also highlights persistent suppression of bone turnover markers and plateauing bone density over time. Study Links https://pubmed.ncbi.nlm.nih.gov/39813642/🦴 Stronger Bones. Healthier Future. I’m Dr. Doug Lucas, and my mission is to help you protect your bones, balance your hormones, and extend your healthspan. On my channel, we focus on osteoporosis prevention, bone strength, hormones, and longevity because strong bones aren’t just about avoiding fractures. They’re the foundation for a longer, healthier life.📚 Join me for a FREE Live Masterclass Want to get your questions answered, hear real-life osteoporosis reversal stories, and learn the 5 Bone Health Mistakes to Avoid? I’ll share proven strategies to build bone density, improve bone quality, and protect your healthspan, straight from my experience as a Board-Certified Orthopedic Surgeon & Osteoporosis Reversal Specialist. 🔗 Register here for FREE: https://www.osteocollective.com/build-bone💻 The OsteoCollective A global community dedicated to bone health & longevity. Learn, connect, and take action: https://www.osteocollective.com Let's connect! Instagram: https://www.instagram.com/dr_douglucas/ Facebook: https://www.facebook.com/doug.lucas.18 LinkedIn: https://www.linkedin.com/in/doug-lucas-b0243522/#osteoporosis #exercise #healthspan

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